Other packages > Find by keyword >

pssmooth  

Flexible and Efficient Evaluation of Principal Surrogates/Treatment Effect Modifiers
View on CRAN: Click here


Download and install pssmooth package within the R console
Install from CRAN:
install.packages("pssmooth")

Install from Github:
library("remotes")
install_github("cran/pssmooth")

Install by package version:
library("remotes")
install_version("pssmooth", "1.0.3")



Attach the package and use:
library("pssmooth")
Maintained by
Michal Juraska
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2018-07-30
Latest Update: 2020-11-18
Description:
Implements estimation and testing procedures for evaluating an intermediate biomarker response as a principal surrogate of a clinical response to treatment (i.e., principal stratification effect modification analysis), as described in Juraska M, Huang Y, and Gilbert PB (2020), Inference on treatment effect modification by biomarker response in a three-phase sampling design, Biostatistics, 21(3): 545-560 . The methods avoid the restrictive 'placebo structural risk' modeling assumption common to past methods and further improve robustness by the use of nonparametric kernel smoothing for biomarker density estimation. A randomized controlled two-group clinical efficacy trial is assumed with an ordered categorical or continuous univariate biomarker response measured at a fixed timepoint post-randomization and with a univariate baseline surrogate measure allowed to be observed in only a subset of trial participants with an observed biomarker response (see the flexible three-phase sampling design in the paper for details). Bootstrap-based procedures are available for pointwise and simultaneous confidence intervals and testing of four relevant hypotheses. Summary and plotting functions are provided for estimation results.
How to cite:
Michal Juraska (2018). pssmooth: Flexible and Efficient Evaluation of Principal Surrogates/Treatment Effect Modifiers. R package version 1.0.3, https://cran.r-project.org/web/packages/pssmooth. Accessed 05 Mar. 2026.
Previous versions and publish date:
1.0.0 (2018-07-30 00:00), 1.0.1 (2018-09-19 22:10), 1.0.2 (2019-01-22 22:50)
Other packages that cited pssmooth R package
View pssmooth citation profile
Other R packages that pssmooth depends, imports, suggests or enhances
Complete documentation for pssmooth
Functions, R codes and Examples using the pssmooth R package
Some associated functions: bootRiskCurve . plotMCEPcurve . riskCurve . summary.riskCurve . testConstancy . testEquality . 
Some associated R codes: pssmooth.R .  Full pssmooth package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

diffIRT  
Diffusion IRT Models for Response and Response Time Data
Package to fit diffusion-based IRT models to response and response time data. Models are fit using ...
Download / Learn more Package Citations See dependency  
pinp  
'pinp' is not 'PNAS'
A 'PNAS'-alike style for 'rmarkdown', derived from the 'Proceedings of the National Academy of Scie ...
Download / Learn more Package Citations See dependency  
ClimClass  
Climate Classification According to Several Indices
Classification of climate according to Koeppen - Geiger, of aridity indices, of continentality indi ...
Download / Learn more Package Citations See dependency  
roccv  
ROC for Cross Validation Results
Cross validate large genetic data while specifying clinical variables that should always be in the m ...
Download / Learn more Package Citations See dependency  
nextGenShinyApps  
Craft Exceptional 'R Shiny' Applications and Dashboards with Novel Responsive Tools
Nove responsive tools for designing and developing 'Shiny' dashboards and applications. The scripts ...
Download / Learn more Package Citations See dependency  
neat  
Efficient Network Enrichment Analysis Test
Includes functions and examples to compute NEAT, the Network Enrichment Analysis Test described in ...
Download / Learn more Package Citations See dependency  

26,264

R Packages

223,360

Dependencies

70,244

Author Associations

26,265

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA