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pocrm  

Dose Finding in Drug Combination Phase I Trials Using PO-CRM
View on CRAN: Click here


Download and install pocrm package within the R console
Install from CRAN:
install.packages("pocrm")

Install from Github:
library("remotes")
install_github("cran/pocrm")

Install by package version:
library("remotes")
install_version("pocrm", "0.13")



Attach the package and use:
library("pocrm")
Maintained by
"Brewer, Ben (arb5mt)"
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2013-03-28
Latest Update: 2021-09-08
Description:
Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
How to cite:
"Brewer, Ben (arb5mt)" (2013). pocrm: Dose Finding in Drug Combination Phase I Trials Using PO-CRM. R package version 0.13, https://cran.r-project.org/web/packages/pocrm. Accessed 25 Aug. 2026.
Previous versions and publish date:
(2026-07-09 06:42), 0.4 (2013-03-28 22:47), 0.5 (2013-05-02 08:13), 0.6 (2013-11-26 22:08), 0.7 (2014-03-11 22:11), 0.8 (2014-07-24 21:42), 0.9 (2015-04-10 01:31), 0.11 (2018-03-03 01:57), 0.12 (2019-03-15 07:40)
Other packages that cited pocrm R package
View pocrm citation profile
Other R packages that pocrm depends, imports, suggests or enhances
Complete documentation for pocrm
Functions, R codes and Examples using the pocrm R package
Some associated functions: getwm . pocrm.imp . pocrm.sim . 
Some associated R codes: getwm.R . pocrm.imp.R . pocrm.sim.R .  Full pocrm package functions and examples
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