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mrMLM  

Multi-Locus Random-SNP-Effect Mixed Linear Model Tools for GWAS
View on CRAN: Click here


Download and install mrMLM package within the R console
Install from CRAN:
install.packages("mrMLM")

Install from Github:
library("remotes")
install_github("cran/mrMLM")

Install by package version:
library("remotes")
install_version("mrMLM", "5.0.1")



Attach the package and use:
library("mrMLM")
Maintained by
Yuan-Ming Zhang
[Scholar Profile | Author Map]
First Published: 2016-02-26
Latest Update: 2022-03-27
Description:
Conduct multi-locus genome-wide association study under the framework of multi-locus random-SNP-effect mixed linear model (mrMLM). First, each marker on the genome is scanned. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers that are potentially associated with the trait are included in a multi-locus genetic model, their effects are estimated by empirical Bayes, and all the nonzero effects were further identified by likelihood ratio test for significant QTL. The program may run on a desktop or laptop computers. If marker genotypes in association mapping population are almost homozygous, these methods in this software are very effective. If there are many heterozygous marker genotypes, the IIIVmrMLM software is recommended. Wen YJ, Zhang H, Ni YL, Huang B, Zhang J, Feng JY, Wang SB, Dunwell JM, Zhang YM, Wu R (2018, ), and Li M, Zhang YW, Zhang ZC, Xiang Y, Liu MH, Zhou YH, Zuo JF, Zhang HQ, Chen Y, Zhang YM (2022, ).
How to cite:
Yuan-Ming Zhang (2016). mrMLM: Multi-Locus Random-SNP-Effect Mixed Linear Model Tools for GWAS. R package version 5.0.1, https://cran.r-project.org/web/packages/mrMLM. Accessed 16 Apr. 2025.
Previous versions and publish date:
1.0 (2016-02-26 14:12), 1.1 (2016-03-06 23:34), 1.2 (2016-04-07 16:00), 1.3 (2016-07-16 09:51), 2.0 (2016-12-20 10:19), 2.1 (2017-02-09 07:02), 3.0 (2018-03-12 05:09), 3.1 (2018-08-26 00:10), 4.0.1 (2020-09-29 16:50), 4.0.2 (2020-10-08 12:50), 4.0 (2019-10-22 10:00), 5.0 (2022-03-18 15:00)
Other packages that cited mrMLM R package
View mrMLM citation profile
Other R packages that mrMLM depends, imports, suggests or enhances
Complete documentation for mrMLM
Functions, R codes and Examples using the mrMLM R package
Some associated functions: DoData . FASTmrEMMA . FASTmrMLM . Gen . Gennotype . ISIS . MultiManhattan . Phe . Phenotype . ReadData . ResultFinal . ResultIntermediate . inputData . mrMLM . mrMLMFun . multiplication_speed . pKWmEB . pLARmEB . 
Some associated R codes: FASTmrEMMA.R . FASTmrMLM.R . ISIS.R . MultiManhattan.R . RcppExports.R . mrMLM.R . mrMLMFun.R . pKWmEB.R . pLARmEB.R .  Full mrMLM package functions and examples
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