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OneArm2stage  

Phase II Single-Arm Two-Stage Designs with Time-to-Event Outcomes
View on CRAN: Click here


Download and install OneArm2stage package within the R console
Install from CRAN:
install.packages("OneArm2stage")

Install from Github:
library("remotes")
install_github("cran/OneArm2stage")

Install by package version:
library("remotes")
install_version("OneArm2stage", "1.2.1")



Attach the package and use:
library("OneArm2stage")
Maintained by
Xiaomeng Yuan
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2022-09-07
Latest Update: 2023-10-09
Description:
Two-stage design for single-arm phase II trials with time-to-event endpoints (e.g., clinical trials on immunotherapies among cancer patients) can be calculated using this package. Two notable advantages of the package: 1) It provides flexible choices from three design methods (optimal, minmax, and admissible), and 2) the power of the design is more accurately calculated using the exact variance in the one-sample log-rank test. The package can be used for 1) planning the sample sizes and other design parameters, and 2) conducting the interim and final analyses for the Go/No-go decisions. More details about the design method can be found in: Wu, J, Chen L, Wei J, Weiss H, Chauhan A. (2020). .
How to cite:
Xiaomeng Yuan (2022). OneArm2stage: Phase II Single-Arm Two-Stage Designs with Time-to-Event Outcomes. R package version 1.2.1, https://cran.r-project.org/web/packages/OneArm2stage. Accessed 05 Jun. 2026.
Previous versions and publish date:
1.1.4 (2022-09-07 10:40), 1.1.5 (2022-12-01 22:20)
Other packages that cited OneArm2stage R package
View OneArm2stage citation profile
Other R packages that OneArm2stage depends, imports, suggests or enhances
Complete documentation for OneArm2stage
Functions, R codes and Examples using the OneArm2stage R package
Some associated functions: FitDat . GenDat_KJ . GenDat_rKJ . LRT . Optimal.KJ . Optimal.rKJ . Sim_KJ . Sim_rKJ . 
Some associated R codes: Sim_KJ.R . Sim_rKJ.R .  Full OneArm2stage package functions and examples
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