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FamEvent  

Family Age-at-Onset Data Simulation and Penetrance Estimation
View on CRAN: Click here


Download and install FamEvent package within the R console
Install from CRAN:
install.packages("FamEvent")

Install from Github:
library("remotes")
install_github("cran/FamEvent")

Install by package version:
library("remotes")
install_version("FamEvent", "3.2")



Attach the package and use:
library("FamEvent")
Maintained by
Yun-Hee Choi
[Scholar Profile | Author Map]
First Published: 2016-02-09
Latest Update: 2024-03-01
Description:
Simulates age-at-onset traits associated with a segregating major gene in family data obtained from population-based, clinic-based, or multi-stage designs. Appropriate ascertainment correction is utilized to estimate age-dependent penetrance functions either parametrically from the fitted model or nonparametrically from the data. The Expectation and Maximization algorithm can infer missing genotypes and carrier probabilities estimated from family's genotype and phenotype information or from a fitted model. Plot functions include pedigrees of simulated families and predicted penetrance curves based on specified parameter values. For more information see Choi, Y.-H., Briollais, L., He, W. and Kopciuk, K. (2021) FamEvent: An R Package for Generating and Modeling Time-to-Event Data in Family Designs, Journal of Statistical Software 97 (7), 1-30.
How to cite:
Yun-Hee Choi (2016). FamEvent: Family Age-at-Onset Data Simulation and Penetrance Estimation. R package version 3.2, https://cran.r-project.org/web/packages/FamEvent. Accessed 29 Mar. 2025.
Previous versions and publish date:
1.0 (2016-02-09 09:46), 1.1 (2016-03-09 15:20), 1.2 (2016-09-30 22:58), 1.3 (2017-03-26 09:30), 2.0 (2019-03-21 06:13), 2.1 (2021-03-17 10:30), 3.0 (2022-11-17 14:00), 3.1 (2024-04-04 01:33)
Other packages that cited FamEvent R package
View FamEvent citation profile
Other R packages that FamEvent depends, imports, suggests or enhances
Complete documentation for FamEvent
Functions, R codes and Examples using the FamEvent R package
Some associated functions: FamEvent-package . LSfam . carrierprob . fampower . penetrance . penetrance_c . penmodel . penmodel_c . penmodelem . penplot . penplot_c . plot.penmodel . plot.penmodel_c . plot.simfam . plot.simfam_c . print.penmodel . print.penmodel_c . print.summary.penmodel . print.summary.penmodel_c . simfam . simfam_c . summary.penmodel . summary.penmodel_c . summary.simfam . summary.simfam_c . 
Some associated R codes: FamilyData-internal.R . MakeRelationship.R . MakeRelationshipExtended.R . Pgene.R . carrierprob.R . carrierprobgeno.R . carrierprobgeno_rev.R . carrierprobpheno_rev.R . cumhaz.R . dlaplace.R . familyDesign.R . familyDesign_c.R . familyDesign_old.R . familyStructure.R . familyStructure_c.R . fampower.R . fgene.R . fgene_c.R . gauss.hermite.R . gh.R . hazards.R . hermite.R . integ_cgamma.R . integ_clognormal.R . integ_frailty.R . integ_nofrailty.R . inv.surv.R . inv.survp.R . inv_surv_c.R . kids.g.R . laplace.R . loglik.vec.R . loglik_frailty.R . loglik_frailty_c.R . loglik_frailty_cgamma.R . loglik_frailty_clognormal.R . loglik_frailty_corr.R . loglik_ind.R . loglik_ind_c.R . loglik_ind_vec.R . mgauss.hermite.R . numericGradient.R . numericNHessian.R . parents.g.R . penetrance.R . penetrance_c.R . penf.R . penf_c.R . penmodel.R . penmodel_c.R . penmodel_old.R . penmodel_rev.R . penmodelem.R . penplot.R . penplot_c.R . plot.penmodel.R . plot.penmodel_c.R . plot.penmodel_old.R . plot.simfam.R . plot.simfam_c.R . print.penmodel.R . print.penmodel_c.R . print.summary.penmodel.R . print.summary.penmodel_c.R . simfam.R . simfam_c.R . summary.penmodel.R . summary.penmodel_c.R . summary.simfam.R . summary.simfam_c.R . surv.dist.R . surv_dist_c.R . survp.dist.R .  Full FamEvent package functions and examples
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