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denovolyzeR  

Statistical Analyses of De Novo Genetic Variants
View on CRAN: Click here


Download and install denovolyzeR package within the R console
Install from CRAN:
install.packages("denovolyzeR")

Install from Github:
library("remotes")
install_github("cran/denovolyzeR")

Install by package version:
library("remotes")
install_version("denovolyzeR", "0.2.0")



Attach the package and use:
library("denovolyzeR")
Maintained by
James Ware
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2015-04-09
Latest Update: 2016-08-01
Description:
An integrated toolset for the analysis of de novo (sporadic) genetic sequence variants. denovolyzeR implements a mutational model that estimates the probability of a de novo genetic variant arising in each human gene, from which one can infer the expected number of de novo variants in a given population size. Observed variant frequencies can then be compared against expectation in a Poisson framework. denovolyzeR provides a suite of functions to implement these analyses for the interpretation of de novo variation in human disease.
How to cite:
James Ware (2015). denovolyzeR: Statistical Analyses of De Novo Genetic Variants. R package version 0.2.0, https://cran.r-project.org/web/packages/denovolyzeR. Accessed 11 Mar. 2026.
Previous versions and publish date:
0.1.0 (2015-04-09 12:03), 0.1.1 (2016-06-18 15:01)
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Complete documentation for denovolyzeR
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