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RARtrials  

Response-Adaptive Randomization in Clinical Trials
View on CRAN: Click here


Download and install RARtrials package within the R console
Install from CRAN:
install.packages("RARtrials")

Install from Github:
library("remotes")
install_github("cran/RARtrials")

Install by package version:
library("remotes")
install_version("RARtrials", "0.0.2")



Attach the package and use:
library("RARtrials")
Maintained by
Chuyao Xu
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2024-06-04
Latest Update: 2025-04-03
Description:
Some response-adaptive randomization methods commonly found in literature are included in this package. These methods include the randomized play-the-winner rule for binary endpoint (Wei and Durham (1978) <doi:10.2307/2286290>), the doubly adaptive biased coin design with minimal variance strategy for binary endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>, Rosenberger and Lachin (2015) <doi:10.1002/9781118742112>) and maximal power strategy targeting Neyman allocation for binary endpoint (Tymofyeyev, Rosenberger, and Hu (2007) <doi:10.1198/016214506000000906>) and RSIHR allocation with each letter representing the first character of the names of the individuals who first proposed this rule (Youngsook and Hu (2010) <doi:10.1198/sbr.2009.0056>, Bello and Sabo (2016) <doi:10.1080/00949655.2015.1114116>), A-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), Aa-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), generalized RSIHR allocation for continuous endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>), Bayesian response-adaptive randomization with a control group using the Thall \& Wathen method for binary and continuous endpoints (Thall and Wathen (2007) <doi:10.1016/j.ejca.2007.01.006>) and the forward-looking Gittins index rule for binary and continuous endpoints (Villar, Wason, and Bowden (2015) <doi:10.1111/biom.12337>, Williamson and Villar (2019) <doi:10.1111/biom.13119>).
How to cite:
Chuyao Xu (2024). RARtrials: Response-Adaptive Randomization in Clinical Trials. R package version 0.0.2, https://cran.r-project.org/web/packages/RARtrials. Accessed 21 Aug. 2026.
Previous versions and publish date:
(2026-07-09 08:18), 0.0.1 (2024-06-04 11:45)
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Complete documentation for RARtrials
Functions, R codes and Examples using the RARtrials R package
Full RARtrials package functions and examples
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