Other packages > Find by keyword >

wnl  

Minimization Tool for Pharmacokinetic-Pharmacodynamic Data Analysis
View on CRAN: Click here


Download and install wnl package within the R console
Install from CRAN:
install.packages("wnl")

Install from Github:
library("remotes")
install_github("cran/wnl")

Install by package version:
library("remotes")
install_version("wnl", "0.8.6")



Attach the package and use:
library("wnl")
Maintained by
Kyun-Seop Bae
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2017-10-16
Latest Update: 2025-03-23
Description:
This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.
How to cite:
Kyun-Seop Bae (2017). wnl: Minimization Tool for Pharmacokinetic-Pharmacodynamic Data Analysis. R package version 0.8.6, https://cran.r-project.org/web/packages/wnl. Accessed 29 Oct. 2026.
Previous versions and publish date:
(2026-07-26 09:50), 0.3.1 (2017-10-16 13:17), 0.3.2 (2017-12-01 05:49), 0.3.3 (2018-03-02 06:19), 0.4.0 (2018-04-02 23:55), 0.4.1 (2018-06-14 13:42), 0.5.0 (2019-05-10 07:50), 0.5.1 (2019-06-10 18:00), 0.6.0 (2020-07-16 06:30), 0.6.1 (2020-08-27 18:10), 0.6.2 (2021-08-07 11:50), 0.6.3 (2021-09-06 06:30), 0.6.4 (2021-11-22 11:20), 0.7.0 (2022-10-28 11:20), 0.7.1 (2022-11-30 01:10), 0.7.2 (2023-03-26 11:00), 0.7.3 (2023-04-25 05:30), 0.8.0 (2024-02-22 07:20), 0.8.1 (2024-06-01 05:10), 0.8.2 (2025-02-21 09:00), 0.8.3 (2025-03-23 04:50), 0.8.4 (2025-09-08 01:30), 0.8.5 (2026-03-07 17:00)
Other packages that cited wnl R package
View wnl citation profile
Other R packages that wnl depends, imports, suggests or enhances
Complete documentation for wnl
Functions, R codes and Examples using the wnl R package
Some associated functions: BasicUtil . Comp1 . DAT . EnvObj . ExpandDH . Objs . Secondary . SolComp2 . SolComp3 . cmpChi . dx . e . hSkew . nComp . nlr . pComp . pProf . wnl-package . wnl5 . 
Some associated R codes: BasicUtil.R . Comp1.R . EnvObj.R . ExpandDH.R . Objs.R . Secondary.R . SolComp2.R . SolComp3.R . cmpChi.R . dx.R . hSkew.R . nComp.R . nlr.R . pComp.R . pProf.R . wnl5.R .  Full wnl package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

GEVcdn  
GEV Conditional Density Estimation Network
Implements a flexible nonlinear modelling framework for nonstationary generalized extreme value anal ...
Download / Learn more Package Citations See dependency  
binovisualfields  
Depth-Dependent Binocular Visual Fields Simulation
Simulation and visualization depth-dependent integrated visual fields. Visual fields are measured mo ...
Download / Learn more Package Citations See dependency  
fastRG  
Sample Generalized Random Dot Product Graphs in Linear Time
Samples generalized random product graphs, a generalization of a broad class of network models. Giv ...
Download / Learn more Package Citations See dependency  
personalized2part  
Two-Part Estimation of Treatment Rules for Semi-Continuous Data
Implements the methodology of Huling, Smith, and Chen (2020) , w ...
Download / Learn more Package Citations See dependency  
nextGenShinyApps  
Craft Exceptional 'R Shiny' Applications and Dashboards with Novel Responsive Tools
Nove responsive tools for designing and developing 'Shiny' dashboards and applications. The scripts ...
Download / Learn more Package Citations See dependency  

29,218

R Packages

247,686

Dependencies

77,281

Author Associations

29,219

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA