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twosigma  

DE Analysis for Single-Cell RNA-Sequencing Data
View on CRAN: Click here


Download and install twosigma package within the R console
Install from CRAN:
install.packages("twosigma")

Install from Github:
library("remotes")
install_github("cran/twosigma")

Install by package version:
library("remotes")
install_version("twosigma", "1.0.2")



Attach the package and use:
library("twosigma")
Maintained by
Eric Van Buren
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2021-12-13
Latest Update: 2021-12-13
Description:
Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) <doi:10.1002/gepi.22361> and Van Buren et al. (2021) <doi:10.1101/2021.01.24.427979>.
How to cite:
Eric Van Buren (2021). twosigma: DE Analysis for Single-Cell RNA-Sequencing Data. R package version 1.0.2, https://cran.r-project.org/web/packages/twosigma. Accessed 07 Oct. 2026.
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