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triggerstrategy  

Trigger Strategy in Clinical Trials
View on CRAN: Click here


Download and install triggerstrategy package within the R console
Install from CRAN:
install.packages("triggerstrategy")

Install from Github:
library("remotes")
install_github("cran/triggerstrategy")

Install by package version:
library("remotes")
install_version("triggerstrategy", "1.2.0")



Attach the package and use:
library("triggerstrategy")
Maintained by
Jiangtao Gou
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2021-05-31
Latest Update: 2023-07-04
Description:
The trigger strategy is a general framework for a multistage statistical design with multiple hypotheses, allowing an adaptive selection of interim analyses. The selection of interim stages can be associated with some prespecified endpoints which serve as the trigger. This selection allows us to refine the critical boundaries in hypotheses testing procedures, and potentially increase the statistical power. This package includes several trial designs using the trigger strategy. See Gou, J. (2023), "Trigger strategy in repeated tests on multiple hypotheses", Statistics in Biopharmaceutical Research, 15(1), 133-140, and Gou, J. (2022), "Sample size optimization and initial allocation of the significance levels in group sequential trials with multiple endpoints", Biometrical Journal, 64(2), 301-311.
How to cite:
Jiangtao Gou (2021). triggerstrategy: Trigger Strategy in Clinical Trials. R package version 1.2.0, https://cran.r-project.org/web/packages/triggerstrategy. Accessed 26 Aug. 2026.
Previous versions and publish date:
(2026-07-09 07:15), 1.0.4 (2021-05-31 10:00), 1.1.0 (2021-06-22 10:10)
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