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tlsR  

Detection and Spatial Analysis of Tertiary Lymphoid Structures
View on CRAN: Click here


Download and install tlsR package within the R console
Install from CRAN:
install.packages("tlsR")

Install from Github:
library("remotes")
install_github("cran/tlsR")

Install by package version:
library("remotes")
install_version("tlsR", "0.3.0")



Attach the package and use:
library("tlsR")
Maintained by
Ali Amiryousefi
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-12-18
Latest Update: 2025-12-18
Description:
Fast, reproducible detection and quantitative analysis of tertiary lymphoid structures (TLS) in multiplexed tissue imaging. Implements Independent Component Analysis Trace (ICAT) index, local Ripley's K scanning, automated K Nearest Neighbor (KNN)-based TLS detection, and T-cell clusters identification as described in Amiryousefi et al. (2025) <doi:10.1101/2025.09.21.677465>.
How to cite:
Ali Amiryousefi (2025). tlsR: Detection and Spatial Analysis of Tertiary Lymphoid Structures. R package version 0.3.0, https://cran.r-project.org/web/packages/tlsR. Accessed 02 Nov. 2026.
Previous versions and publish date:
(2026-07-09 07:14), 0.1.2 (2025-12-18 15:40), 0.2.0 (2026-04-09 19:00)
Other packages that cited tlsR R package
View tlsR citation profile
Other R packages that tlsR depends, imports, suggests or enhances
Complete documentation for tlsR
Functions, R codes and Examples using the tlsR R package
Full tlsR package functions and examples
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