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titeIR  

Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities
View on CRAN: Click here


Download and install titeIR package within the R console
Install from CRAN:
install.packages("titeIR")

Install from Github:
library("remotes")
install_github("cran/titeIR")

Install by package version:
library("remotes")
install_version("titeIR", "0.1.0")



Attach the package and use:
library("titeIR")
Maintained by
Lee McDaniel
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2018-09-28
Latest Update: 2018-09-28
Description:
Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.
How to cite:
Lee McDaniel (2018). titeIR: Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities. R package version 0.1.0, https://cran.r-project.org/web/packages/titeIR. Accessed 22 Dec. 2024.
Previous versions and publish date:
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Complete documentation for titeIR
Functions, R codes and Examples using the titeIR R package
Some associated functions: isotitedose . isotitesim . 
Some associated R codes: isodose.R . isosim.R .  Full titeIR package functions and examples
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