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strata.MaxCombo  

Stratified Max-Combo Test
View on CRAN: Click here


Download and install strata.MaxCombo package within the R console
Install from CRAN:
install.packages("strata.MaxCombo")

Install from Github:
library("remotes")
install_github("cran/strata.MaxCombo")

Install by package version:
library("remotes")
install_version("strata.MaxCombo", "0.0.1")



Attach the package and use:
library("strata.MaxCombo")
Maintained by
Yuwen Liu
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2023-07-16
Latest Update: 2023-07-16
Description:
Non-proportional hazard (NPH) is commonly observed in immuno-oncology studies, where the survival curves of the treatment and control groups show delayed separation. To properly account for NPH, several statistical methods have been developed. One such method is Max-Combo test, which is a straightforward and flexible hypothesis testing method that can simultaneously test for constant, early, middle, and late treatment effects. However, the majority of the Max-Combo test performed in clinical studies are unstratified, ignoring the important prognostic stratification factors. To fill this gap, we have developed an R package for stratified Max-Combo testing that accounts for stratified baseline factors. Our package explores various methods for calculating combined test statistics, estimating joint distributions, and determining the p-values.
How to cite:
Yuwen Liu (2023). strata.MaxCombo: Stratified Max-Combo Test. R package version 0.0.1, https://cran.r-project.org/web/packages/strata.MaxCombo. Accessed 06 Mar. 2026.
Previous versions and publish date:
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Complete documentation for strata.MaxCombo
Functions, R codes and Examples using the strata.MaxCombo R package
Some associated functions: SMCtest . WLRtest . sim_data . 
Some associated R codes: SMCtest.R . WLRtest.R . sim_data.R .  Full strata.MaxCombo package functions and examples
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