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ssMutPA  

Single-Sample Mutation-Based Pathway Analysis
View on CRAN: Click here


Download and install ssMutPA package within the R console
Install from CRAN:
install.packages("ssMutPA")

Install from Github:
library("remotes")
install_github("cran/ssMutPA")

Install by package version:
library("remotes")
install_version("ssMutPA", "0.1.2")



Attach the package and use:
library("ssMutPA")
Maintained by
Junwei Han
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2024-04-16
Latest Update: 2024-04-16
Description:
A systematic bioinformatics tool to perform single-sample mutation-based pathway analysis by integrating somatic mutation data with the Protein-Protein Interaction (PPI) network. In this method, we use local and global weighted strategies to evaluate the effects of network genes from mutations according to the network topology and then calculate the mutation-based pathway enrichment score (ssMutPES) to reflect the accumulated effect of mutations of each pathway. Subsequently, the ssMutPES profiles are used for unsupervised spectral clustering to identify cancer subtypes.
How to cite:
Junwei Han (2024). ssMutPA: Single-Sample Mutation-Based Pathway Analysis. R package version 0.1.2, https://cran.r-project.org/web/packages/ssMutPA. Accessed 22 Dec. 2024.
Previous versions and publish date:
0.1.0 (2024-04-16 16:50), 0.1.1 (2024-10-10 17:00)
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Complete documentation for ssMutPA
Functions, R codes and Examples using the ssMutPA R package
Full ssMutPA package functions and examples
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