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simFastBOIN
View on CRAN: Click
here
Download and install simFastBOIN package within the R console
Install from CRAN:
install.packages("simFastBOIN")
Install from Github:
library("remotes")
install_github("cran/simFastBOIN") Install by package version:
library("remotes")
install_version("simFastBOIN", "2.0.0") Attach the package and use:
library("simFastBOIN")
Maintained by
Gosuke Homma
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[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-12-17
Latest Update: 2025-12-17
Description:
Conducting Bayesian Optimal Interval (BOIN) design for phase I dose-finding trials. 'simFastBOIN' provides functions for pre-computing decision tables, conducting trial simulations, and evaluating operating characteristics. The package uses vectorized operations and the Iso::pava() function for isotonic regression to achieve efficient performance while maintaining full compatibility with BOIN methodology. Version 1.3.2 adds p_saf and p_tox parameters for customizable safety and toxicity thresholds. Version 1.3.1 fixes Date field. Version 1.2.1 adds comprehensive 'roxygen2' documentation and enhanced print formatting with flexible table output options. Version 1.2.0 integrated C-based PAVA for isotonic regression. Version 1.1.0 introduced conservative MTD selection (boundMTD) and flexible early stopping rules (n_earlystop_rule). Methods are described in Liu and Yuan (2015) <doi:10.1111/rssc.12089>.
How to cite:
Gosuke Homma (2025). simFastBOIN: Fast Simulation of Bayesian Optimal Interval Designs for Phase I Trials. R package version 2.0.0, https://cran.r-project.org/web/packages/simFastBOIN. Accessed 25 Oct. 2026.
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