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scDiffCom  

Differential Analysis of Intercellular Communication from scRNA-Seq Data
View on CRAN: Click here


Download and install scDiffCom package within the R console
Install from CRAN:
install.packages("scDiffCom")

Install from Github:
library("remotes")
install_github("cran/scDiffCom")

Install by package version:
library("remotes")
install_version("scDiffCom", "1.2.0")



Attach the package and use:
library("scDiffCom")
Maintained by
Cyril Lagger
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2021-08-17
Latest Update: 2023-11-03
Description:
Analysis tools to investigate changes in intercellular communication from scRNA-seq data. Using a Seurat object as input, the package infers which cell-cell interactions are present in the dataset and how these interactions change between two conditions of interest (e.g. young vs old). It relies on an internal database of ligand-receptor interactions (available for human, mouse and rat) that have been gathered from several published studies. Detection and differential analyses rely on permutation tests. The package also contains several tools to perform over-representation analysis and visualize the results. See Lagger, C. et al. (2023) for a full description of the methodology.
How to cite:
Cyril Lagger (2021). scDiffCom: Differential Analysis of Intercellular Communication from scRNA-Seq Data. R package version 1.2.0, https://cran.r-project.org/web/packages/scDiffCom. Accessed 25 Jun. 2026.
Previous versions and publish date:
0.1.0 (2021-08-17 09:20), 1.0.0 (2023-11-03 19:40)
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Complete documentation for scDiffCom
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