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rxode2  

Facilities for Simulating from ODE-Based Models
View on CRAN: Click here


Download and install rxode2 package within the R console
Install from CRAN:
install.packages("rxode2")

Install from Github:
library("remotes")
install_github("cran/rxode2")

Install by package version:
library("remotes")
install_version("rxode2", "5.0.1")



Attach the package and use:
library("rxode2")
Maintained by
Matthew L. Fidler
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2022-05-09
Latest Update: 2025-07-24
Description:
Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.
How to cite:
Matthew L. Fidler (2022). rxode2: Facilities for Simulating from ODE-Based Models. R package version 5.0.1, https://cran.r-project.org/web/packages/rxode2. Accessed 05 Mar. 2026.
Previous versions and publish date:
2.0.6 (2022-05-09 09:00), 2.0.7 (2022-09-23 16:49), 2.0.8 (2022-09-23 04:50), 2.0.9 (2022-10-19 13:00), 2.0.10 (2022-10-20 23:12), 2.0.11 (2022-11-01 22:45), 2.0.12 (2023-03-28 08:30), 2.0.13 (2023-04-22 09:40), 2.0.14 (2023-10-07 07:00), 2.1.0 (2023-12-11 23:40), 2.1.1 (2023-12-13 10:50), 2.1.2 (2024-01-31 00:30), 2.1.3 (2024-05-28 11:30), 3.0.0 (2024-09-18 15:10), 3.0.1 (2024-09-22 23:20), 3.0.2 (2024-10-30 06:30), 3.0.3 (2024-12-15 07:10), 3.0.4 (2025-02-14 17:20), 4.0.0 (2025-07-16 06:10), 4.0.1 (2025-07-18 02:10), 4.0.2 (2025-07-21 07:10), 4.0.3 (2025-07-24 17:10), 4.1.0 (2025-08-29 20:20), 4.1.1 (2025-10-08 07:10), 5.0.0 (2025-11-28 10:40)
Other packages that cited rxode2 R package
View rxode2 citation profile
Other R packages that rxode2 depends, imports, suggests or enhances
Complete documentation for rxode2
Functions, R codes and Examples using the rxode2 R package
Some associated functions: as.ini . as.model . as.rxUi . assertRxUi . binomProbs . coef.rxode2 . dot-assertRenameErrorModelLine . dot-copyUi . dot-handleSingleErrTypeNormOrTFoceiBase . dot-iniGetAppendArg . dot-iniHandleAppend . dot-iniHandleLine . dot-matchesLangTemplate . dot-minfo . dot-modelHandleModelLines . dot-quoteCallInfoLines . dot-rxDocTable . dot-rxGetHiBoundaryPred1AndIni . dot-rxGetLambdaFromPred1AndIni . dot-rxGetLowBoundaryPred1AndIni . dot-rxGetPredictionDVTransform . dot-rxGetPredictionF . dot-rxGetPredictionFTransform . dot-rxGetVarianceForErrorType . dot-rxIsLinCmt . dot-rxJacobian . dot-rxLinCmtGen . dot-rxPrune . dot-rxSens . dot-rxWithOptions . dot-rxWithSink . dot-rxWithWd . dot-useUtf . erf . etTrans . findLhs . gammap . gammapDer . gammapInv . gammaq . gammaqInv . genShinyApp.template . getBaseIniSimModel . getBaseSimModel . getBaseSymengineModel . getRxThreads . guide_none . ini-set . ini . is.rxSolve . llikBeta . llikBinom . llikCauchy . llikChisq . llikExp . llikF . llikGamma . llikGeom . llikNbinom . llikNbinomMu . llikNorm . llikPois . llikT . llikUnif . llikWeibull . logit . lowergamma . meanProbs . model-set . model . modelExtract . odeMethodToInt . plot.rxSolve . plus-.rxSolve . print.rxCoef . print.rxDll . print.rxode2 . probit . reexports . rxAllowUnload . rxAppendModel . rxAssignControlValue . rxAssignPtr . rxBlockZeros . rxC . rxCat . rxChain . rxChain2 . rxClean . rxCombineErrorLines . rxCompile . rxCondition . rxControlUpdateSens . rxCreateCache . rxD . rxDelete . rxDemoteAddErr . rxDfdy . rxDll . rxDynLoad . rxDynUnload . rxErrTypeCombine . rxExpandFEta_ . rxExpandGrid . rxExpandGrid_ . rxExpandIfElse . rxExpandSens2_ . rxExpandSens_ . rxForget . rxFun . rxGetControl . rxGetDistributionSimulationLines . rxGetLin . rxGetModel . rxGetrxode2 . rxHtml . rxIndLinState . rxIndLinStrategy . rxIndLin_ . rxInits . rxInv . rxIs . rxIsCurrent . rxIsLoaded . rxLhs . rxLock . rxMd5 . rxModelVars . rxModels_ . rxNorm . rxOptExpr . rxParams . rxParseErr . rxParsePk . rxParsePred . rxPkg . rxPp . rxPreferredDistributionName . rxProgress . rxPrune . rxReload . rxRemoveControl . rxRename . rxRepR0_ . rxReservedKeywords . rxResidualError . rxS . rxSetControl . rxSetCovariateNamesForPiping . rxSetPipingAuto . rxSetProd . rxSetProgressBar . rxSetSilentErr . rxSetSum . rxSetupIni . rxSetupScale . rxShiny . rxSimThetaOmega . rxSolve . rxSolveFree . rxSplitPlusQ . rxState . rxSumProdModel . rxSupportedFuns . rxSuppressMsg . rxSymInvChol . rxSymInvCholCreate . rxSymInvCholN . rxSyncOptions . rxSyntaxFunctions . rxTempDir . rxTheme . rxToSE . rxTrans . rxUiDecompress . rxUiGet . rxUnloadAll . rxUse . rxValidate . rxVersion . rxbeta . rxbinom . rxcauchy . rxchisq . rxexp . rxf . rxgamma . rxgeom . rxnbinom . rxnormV . rxode2-set . rxode2 . rxord . rxpois . rxt . rxunif . rxweibull . stat_amt . stat_cens . summary.rxDll . summary.rxode2 . update.rxUi . uppergamma . zeroRe . 
Some associated R codes: DollarNames.R . RcppExports.R . asFunction.R . asIni.R . asModel.R . asRxui.R . assert.R . build.R . confint.R . dsl.R . err-foceiBase.R . err-sim.R . err.R . fixef.R . format.R . genShinyApp.template.R . geom-amt.R . geom-cens.R . getBaseSim.R . llik.R . modelExtract.R . modlib.R . mu-cov-downgrade.R . mu.R . nearpd.R . piping-ini.R . piping-model.R . piping-update.R . piping.R . plot.R . print.R . progress.R . reexport.R . rxFormat.R . rxIndLin.R . rxJacobian.R . rxLinCmt.R . rxOptExpr.R . rxParams.R . rxPrune.R . rxReservedKeywords.R . rxResidualError.R . rxShiny.R . rxSymInv.R . rxSyntaxFunctions.R . rxUiBlessed.R . rxUiGet.R . rxValidate.R . rxode-options.R . rxode2.R . rxode2_md5.R . rxrandom.R . rxsolve.R . str.R . summary.R . symengine.R . ui-assign-parts.R . ui-bind.R . ui-getControl.R . ui-rename.R . ui.R . units.R . utils.R . version.R .  Full rxode2 package functions and examples
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