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revert  

Reversion Mutation Identifier for Sequencing Data
View on CRAN: Click here


Download and install revert package within the R console
Install from CRAN:
install.packages("revert")

Install from Github:
library("remotes")
install_github("cran/revert")

Install by package version:
library("remotes")
install_version("revert", "0.0.1")



Attach the package and use:
library("revert")
Maintained by
Hui Xiao
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2023-11-23
Latest Update: 2023-11-23
Description:
A tool for detecting reversions for a given pathogenic mutation from next-generation DNA sequencing data. It analyses reads aligned to the locus of the pathogenic mutation and reports reversion events where secondary mutations have restored or undone the deleterious effect of the original pathogenic mutation, e.g., secondary indels complement to a frameshift pathogenic mutation converting the orignal frameshift mutation into inframe mutaions, deletions or SNVs that replaced the original pathogenic mutation restoring the open reading frame, SNVs changing the stop codon caused by the original nonsense SNV into an amino acid, etc.
How to cite:
Hui Xiao (2023). revert: Reversion Mutation Identifier for Sequencing Data. R package version 0.0.1, https://cran.r-project.org/web/packages/revert. Accessed 30 Jan. 2025.
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Complete documentation for revert
Functions, R codes and Examples using the revert R package
Some associated functions: getReversions . 
Some associated R codes: getReversions.R . helpers.R .  Full revert package functions and examples
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