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phase1PRMD  

Personalized Repeated Measurement Design for Phase I Clinical Trials
View on CRAN: Click here


Download and install phase1PRMD package within the R console
Install from CRAN:
install.packages("phase1PRMD")

Install from Github:
library("remotes")
install_github("cran/phase1PRMD")

Install by package version:
library("remotes")
install_version("phase1PRMD", "1.0.2")



Attach the package and use:
library("phase1PRMD")
Maintained by
Lu Zhang
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2019-02-03
Latest Update: 2020-03-09
Description:
Implements Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints and longitudinal efficacy measure from multiple treatment cycles. The package provides flags to fit a variety of model-based phase I design, including 1 stage models with or without individualized dose modification, 3-stage models with or without individualized dose modification, etc. Functions are provided to recommend dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) .
How to cite:
Lu Zhang (2019). phase1PRMD: Personalized Repeated Measurement Design for Phase I Clinical Trials. R package version 1.0.2, https://cran.r-project.org/web/packages/phase1PRMD. Accessed 21 Nov. 2024.
Previous versions and publish date:
1.0.1 (2019-02-03 18:00)
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