Other packages > Find by keyword >

ordcrm  

Likelihood-Based Continual Reassessment Method (CRM) Dose Finding Designs
View on CRAN: Click here


Download and install ordcrm package within the R console
Install from CRAN:
install.packages("ordcrm")

Install from Github:
library("remotes")
install_github("cran/ordcrm")

Install by package version:
library("remotes")
install_version("ordcrm", "1.0.0")



Attach the package and use:
library("ordcrm")
Maintained by
Emily V. Dressler
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2016-11-04
Latest Update: 2016-11-04
Description:
Provides the setup and calculations needed to run a likelihood-based continual reassessment method (CRM) dose finding trial and performs simulations to assess design performance under various scenarios. 3 dose finding designs are included in this package: ordinal proportional odds model (POM) CRM, ordinal continuation ratio (CR) model CRM, and the binary 2-parameter logistic model CRM. These functions allow customization of design characteristics to vary sample size, cohort sizes, target dose-limiting toxicity (DLT) rates, discrete or continuous dose levels, combining ordinal grades 0 and 1 into one category, and incorporate safety and/or stopping rules. For POM and CR model designs, ordinal toxicity grades are specified by common terminology criteria for adverse events (CTCAE) version 4.0. Function 'pseudodata' creates the necessary starting models for these 3 designs, and function 'nextdose' estimates the next dose to test in a cohort of patients for a target DLT rate. We also provide the function 'crmsimulations' to assess the performance of these 3 dose finding designs under various scenarios.
How to cite:
Emily V. Dressler (2016). ordcrm: Likelihood-Based Continual Reassessment Method (CRM) Dose Finding Designs. R package version 1.0.0, https://cran.r-project.org/web/packages/ordcrm. Accessed 08 Mar. 2026.
Previous versions and publish date:
No previous versions
Other packages that cited ordcrm R package
View ordcrm citation profile
Other R packages that ordcrm depends, imports, suggests or enhances
Complete documentation for ordcrm
Functions, R codes and Examples using the ordcrm R package
Some associated functions: crmsimulations . nextdose . pseudodata . 
Some associated R codes: constraints.R . crmsimulations.R . fiterations.R . nextdose.R . pseudodata.R .  Full ordcrm package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

quickcode  
Quick and Essential 'R' Tricks for Better Scripts
The NOT functions, 'R' tricks and a compilation of some simple quick plus often used 'R' codes to im ...
Download / Learn more Package Citations See dependency  
candisc  
Visualizing Generalized Canonical Discriminant and Canonical Correlation Analysis
Functions for computing and visualizing generalized canonical discriminant analyses and canonical c ...
Download / Learn more Package Citations See dependency  
vars  
VAR Modelling
Estimation, lag selection, diagnostic testing, forecasting, causality analysis, forecast error varia ...
Download / Learn more Package Citations See dependency  
ptycho  
Bayesian Variable Selection with Hierarchical Priors
Bayesian variable selection for linear regression models using hierarchical priors. There is a pr ...
Download / Learn more Package Citations See dependency  
generator  
Generate Data Containing Fake Personally Identifiable Information
Allows users to quickly and easily generate fake data containing Personally Identifiable Informatio ...
Download / Learn more Package Citations See dependency  

26,270

R Packages

223,360

Dependencies

70,376

Author Associations

26,265

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA