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nlmixr2extra  

Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions
View on CRAN: Click here


Download and install nlmixr2extra package within the R console
Install from CRAN:
install.packages("nlmixr2extra")

Install from Github:
library("remotes")
install_github("cran/nlmixr2extra")

Install by package version:
library("remotes")
install_version("nlmixr2extra", "5.0.0")



Attach the package and use:
library("nlmixr2extra")
Maintained by
Matthew Fidler
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2022-05-17
Latest Update: 2025-02-17
Description:
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 ). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 ). This package is for support functions like preconditioned fits , boostrap and stepwise covariate selection.
How to cite:
Matthew Fidler (2022). nlmixr2extra: Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions. R package version 5.0.0, https://cran.r-project.org/web/packages/nlmixr2extra. Accessed 14 Jul. 2026.
Previous versions and publish date:
(2026-07-09 06:25), 2.0.6 (2022-05-17 11:20), 2.0.7 (2022-10-20 01:22), 2.0.8 (2022-10-23 00:32), 2.0.9 (2024-01-31 15:00), 2.0.10 (2024-05-29 22:50), 3.0.0 (2024-09-18 18:50), 3.0.1 (2024-10-29 19:00), 3.0.2 (2025-02-17 06:40), 5.0.0 (2025-11-29 07:10)
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