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multiDEGGs  

Multi-Omic Differentially Expressed Gene-Gene Pairs
View on CRAN: Click here


Download and install multiDEGGs package within the R console
Install from CRAN:
install.packages("multiDEGGs")

Install from Github:
library("remotes")
install_github("cran/multiDEGGs")

Install by package version:
library("remotes")
install_version("multiDEGGs", "1.1.2")



Attach the package and use:
library("multiDEGGs")
Maintained by
Elisabetta Sciacca
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-06-05
Latest Update: 2025-07-29
Description:
Performs multi-omic differential network analysis by revealing differential interactions between molecular entities (genes, proteins, transcription factors, or other biomolecules) across the omic datasets provided. For each omic dataset, a differential network is constructed where links represent statistically significant differential interactions between entities. These networks are then integrated into a comprehensive visualization using distinct colors to distinguish interactions from different omic layers. This unified display allows interactive exploration of cross-omic patterns, such as differential interactions present at both transcript and protein levels. For each link, users can access differential statistical significance metrics (p values or adjusted p values, calculated via robust or traditional linear regression with interaction term) and differential regression plots. The methods implemented in this package are described in Sciacca et al. (2023) <doi:10.1093/bioinformatics/btad192>.
How to cite:
Elisabetta Sciacca (2025). multiDEGGs: Multi-Omic Differentially Expressed Gene-Gene Pairs. R package version 1.1.2, https://cran.r-project.org/web/packages/multiDEGGs. Accessed 07 Mar. 2026.
Previous versions and publish date:
1.0.0 (2025-06-05 13:10), 1.1.0 (2025-07-29 18:30), 1.1.1 (2025-10-24 10:10), 1.1.2 (2026-01-16 01:40)
Other packages that cited multiDEGGs R package
View multiDEGGs citation profile
Other R packages that multiDEGGs depends, imports, suggests or enhances
Complete documentation for multiDEGGs
Functions, R codes and Examples using the multiDEGGs R package
Full multiDEGGs package functions and examples
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