R package citation, R package reverse dependencies, R package scholars, install an r package from GitHub hy is package acceptance pending why is package undeliverable amazon why is package on hold dhl tour packages why in r package r and r package full form why is r free why r is bad which r package to install which r package has which r package which r package version which r package readxl which r package ggplot which r package fread which r package license where is package.json where is package-lock.json where is package.swift where is package explorer in eclipse where is package where is package manager unity where is package installer android where is package manager console in visual studio who r package which r package to install which r package version who is package who is package deal who is package design r and r package full form r and r package meaning what r package has what package r what is package in java what is package what is package-lock.json what is package in python what is package.json what is package installer do r package can't install r packages r can't find package r can't load package can't load xlsx package r can't install psych package r can't install sf package r Write if else in NONMEM pk pd
molnet
View on CRAN: Click
here
Download and install molnet package within the R console
Install from CRAN:
install.packages("molnet")
Install from Github:
library("remotes")
install_github("cran/molnet")
Install by package version:
library("remotes")
install_version("molnet", "0.1.0")
Attach the package and use:
library("molnet")
Maintained by
Katharina Baum
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
First Published: 2021-08-06
Latest Update: 2021-08-06
Description:
Networks provide a means to incorporate molecular interactions into
reasoning, but on the omics-level, they are currently mainly used to combine
genomic and proteomic information. We here present a novel network analysis
pipeline that enables integrative analysis of multi-omics data including
metabolomics. It allows for comparative conclusions between two different
conditions, such as tumor subgroups, healthy vs. disease, or generally control
vs. perturbed.
Our approach focuses on interactions and their strength instead of on node
properties and includes molecules with low abundance and unknown function. We
use correlation-induced networks that are reduced and combined to form
heterogeneous, multi-omics molecular networks. Prior information such as
metabolite-protein interactions are incorporated. A semi-local, path-based
integration step denoises the network and ensures integrative conclusions. As
case studies, we investigate differential drug response in breast cancer tumor
datasets providing proteomics, transcriptomics, phospho-proteomics and
metabolomics data and contrasting patients with different estrogen receptor
status.
Our proposed pipeline leverages multi-omics data for differential predictions,
e.g. on drug response, and includes prior information on interactions.
The case study presented in the vignette uses data published by
Krug (2020) . The package license applies only
to the software and explicitly not to the included data.
How to cite:
Katharina Baum (2021). molnet: Predicting Differential Drug Response using Multi-Omics Networks. R package version 0.1.0, https://cran.r-project.org/web/packages/molnet. Accessed 23 Apr. 2025.
Previous versions and publish date:
0.1.0 (2021-08-06 10:30)
Other packages that cited molnet R package
View molnet citation profile
Other R packages that molnet depends,
imports, suggests or enhances
Functions, R codes and Examples using
the molnet R package
Some associated functions: calculate_interaction_score . check_connection . check_drug_target . check_drug_targets_in_layers . check_input . check_layer . check_sensible_connections . chunk . chunk_2gether . combine_graphs . combined_graphs_example . corPvalueStudentParallel . create_unique_layer_node_ids . determine_drug_targets . differential_score . differential_score_graph_example . drug_gene_interactions . drug_response_score_example . drug_target_interaction_example . drug_targets_example . find_targets . generate_combined_graphs . generate_individual_graphs . generate_reduced_graph . get_drug_response_score . get_layer . get_layer_setting . graph_metrics . individual_graphs_example . install_python_dependencies . inter_layer_edgelist_by_id . inter_layer_edgelist_by_table . interaction_score . interaction_score_graphs_example . interaction_score_graphs_vignette . layers_example . load_interaction_score_output . make_connection . make_drug_target . make_layer . metabolite_data . metabolite_protein_interaction . molnet_settings . mrna_data . network_reduction_by_p_value . network_reduction_by_pickHardThreshold . phosphoprotein_data . pickHardThreshold_alternative . pipe . protein_data . return_errors . sample_size . scaleFreeFitIndex_alternative . set_cluster . shutdown_cluster . start_pipeline . target_edge_list . write_interaction_score_input .
Some associated R codes: alternative_pickHardThreshold.R . checks.R . data_documentations.R . drug_targets.R . graph_combination.R . interaction_score.R . network_generation.R . network_reduction.R . pipeline_functions.R . settings.R . utilities.R . utils-pipe.R . Full molnet package functions and examples
Downloads during the last 30 days
Today's Hot Picks in Authors and Packages
sociome
Accesses raw data via API and calculates social determinants of health measures for user-specified l ...
Download / Learn more Package Citations See dependency
Download / Learn more Package Citations See dependency
Maintainer: Nik Krieger (view profile)
miCoPTCM
Fits Semiparametric Promotion Time Cure Models, taking into account (using a
corrected score approa ...
Download / Learn more Package Citations See dependency
Download / Learn more Package Citations See dependency
Maintainer: Aurelie Bertrand (view profile)
ODEnetwork
Simulates a network of ordinary differential equations of order
two. The package provides an easy i ...
Download / Learn more Package Citations See dependency
Download / Learn more Package Citations See dependency
Maintainer: Dirk Surmann (view profile)
GenomeAdapt
Portable, scalable and highly computationally efficient tool for detecting signatures of local adapt ...
Download / Learn more Package Citations See dependency
Download / Learn more Package Citations See dependency
Maintainer: Xinghu Qin (view profile)
BLRShiny2
An interactive document on the topic of binary logistic regression analysis using 'rmarkdown' and ...
Download / Learn more Package Citations See dependency
Download / Learn more Package Citations See dependency
Maintainer: Kartikeya Bolar (view profile)
nextGenShinyApps
Nove responsive tools for designing and developing 'Shiny' dashboards and applications. The scripts ...
Download / Learn more Package Citations See dependency
Download / Learn more Package Citations See dependency
Maintainer: Obinna Obianom (view profile)
24,098
R Packages
207,311
Dependencies
65,069
Author Associations
24,099
Publication Badges
