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mectx  

MEchanistic Clustering - Treatment eXposure Framework
View on CRAN: Click here


Download and install mectx package within the R console
Install from CRAN:
install.packages("mectx")

Install from Github:
library("remotes")
install_github("cran/mectx")

Install by package version:
library("remotes")
install_version("mectx", "1.1.1")



Attach the package and use:
library("mectx")
Maintained by
Dipankor Dhrubo
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2026-05-11
Latest Update: 2026-05-11
Description:
Implements the MEC-TX (MEchanistic Clustering - Treatment eXposure) framework for encoding, clustering, and survival analysis of real-world oncology treatment timelines. Provides functions for normalising medication records, computing treatment intervals, performing k-means clustering in PCA space, assigning line-of-therapy labels, and comparing survival outcomes across treatment groups. Designed for use with registry-based cohorts such as the ORIEN AVATAR dataset. Methods follow the digital-twin framework described in Dhrubo and Spakowicz (2026) <https://github.com/spakowiczlab/mec-tx>. treatment timelines using the MEC-TX digital-twin framework.
How to cite:
Dipankor Dhrubo (2026). mectx: MEchanistic Clustering - Treatment eXposure Framework. R package version 1.1.1, https://cran.r-project.org/web/packages/mectx. Accessed 12 Sep. 2026.
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Functions, R codes and Examples using the mectx R package
Full mectx package functions and examples
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