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invitroTKstats  

In Vitro Toxicokinetic Data Processing and Analysis Pipeline
View on CRAN: Click here


Download and install invitroTKstats package within the R console
Install from CRAN:
install.packages("invitroTKstats")

Install from Github:
library("remotes")
install_github("cran/invitroTKstats")

Install by package version:
library("remotes")
install_version("invitroTKstats", "0.0.14")



Attach the package and use:
library("invitroTKstats")
Maintained by
Sarah E. Davidson-Fritz
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-08-19
Latest Update: 2025-08-19
Description:
A set of tools for processing and analyzing in vitro toxicokinetic measurements in a standardized and reproducible pipeline. The package was developed to perform frequentist and Bayesian estimation on a variety of in vitro toxicokinetic measurements including – but not limited to – chemical fraction unbound in the presence of plasma (f_up), intrinsic hepatic clearance (Clint, uL/min/million hepatocytes), and membrane permeability for oral absorption (Caco2). The methods provided by the package were described in Wambaugh et al. (2019) <doi:10.1093/toxsci/kfz205>.
How to cite:
Sarah E. Davidson-Fritz (2025). invitroTKstats: In Vitro Toxicokinetic Data Processing and Analysis Pipeline. R package version 0.0.14, https://cran.r-project.org/web/packages/invitroTKstats. Accessed 24 Oct. 2026.
Previous versions and publish date:
(2026-07-09 07:50), 0.0.13 (2025-08-19 17:00)
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Complete documentation for invitroTKstats
Functions, R codes and Examples using the invitroTKstats R package
Full invitroTKstats package functions and examples
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