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insulin.secretion  

Insulin Secretion Rate Deconvolution
View on CRAN: Click here


Download and install insulin.secretion package within the R console
Install from CRAN:
install.packages("insulin.secretion")

Install from Github:
library("remotes")
install_github("cran/insulin.secretion")

Install by package version:
library("remotes")
install_version("insulin.secretion", "0.0.2")



Attach the package and use:
library("insulin.secretion")
Maintained by
Ken Stier
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-11-05
Latest Update: 2025-11-05
Description:
Calculates insulin secretion rates from C-peptide values based on the methods described in Van Cauter et al. (1992) <doi:10.2337/diab.41.3.368>. Includes functions to calculate estimated insulin secretion rates using linear or cubic spline interpolation of c-peptide values (see Eaton et al., 1980 <doi:10.1210/jcem-51-3-520> and Polonsky et al., 1986 <doi:10.1172/JCI112308>) and to calculate estimates of input coefficients (volume of distribution, short half life, long half life, and fraction attributed to short half life) as described by Van Cauter. Although the generated coefficients are specific to insulin secretion, the two-compartment secretion model used here is useful for certain applications beyond insulin.
How to cite:
Ken Stier (2025). insulin.secretion: Insulin Secretion Rate Deconvolution. R package version 0.0.2, https://cran.r-project.org/web/packages/insulin.secretion. Accessed 04 Oct. 2026.
Previous versions and publish date:
(2026-07-09 07:49), 0.0.1 (2025-11-05 21:20)
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Complete documentation for insulin.secretion
Functions, R codes and Examples using the insulin.secretion R package
Full insulin.secretion package functions and examples
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