Other packages > Find by keyword >

esDesign  

Adaptive Enrichment Designs with Sample Size Re-Estimation
View on CRAN: Click here


Download and install esDesign package within the R console
Install from CRAN:
install.packages("esDesign")

Install from Github:
library("remotes")
install_github("cran/esDesign")

Install by package version:
library("remotes")
install_version("esDesign", "1.0.3")



Attach the package and use:
library("esDesign")
Maintained by
Zhao Yang
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2018-08-10
Latest Update: 2021-07-13
Description:
Software of 'esDesign' is developed to implement the adaptive enrichment designs with sample size re-estimation presented in Lin et al. (2021) . In details, three-proposed trial designs are provided, including the AED1-SSR (or ES1-SSR), AED2-SSR (or ES2-SSR) and AED3-SSR (or ES3-SSR). In addition, this package also contains several widely used adaptive designs, such as the Marker Sequential Test (MaST) design proposed Freidlin et al. (2014) , the adaptive enrichment designs without early stopping (AED or ES), the sample size re-estimation procedure (SSR) based on the conditional power proposed by Proschan and Hunsberger (1995), and some useful functions. In details, we can calculate the futility and/or efficacy stopping boundaries, the sample size required, calibrate the value of the threshold of the difference between subgroup-specific test statistics, conduct the simulation studies in AED, SSR, AED1-SSR, AED2-SSR and AED3-SSR.
How to cite:
Zhao Yang (2018). esDesign: Adaptive Enrichment Designs with Sample Size Re-Estimation. R package version 1.0.3, https://cran.r-project.org/web/packages/esDesign. Accessed 27 Jun. 2026.
Previous versions and publish date:
1.0.0 (2018-08-10 18:30), 1.0.2 (2018-11-23 06:50)
Other packages that cited esDesign R package
View esDesign citation profile
Other R packages that esDesign depends, imports, suggests or enhances
Complete documentation for esDesign
Functions, R codes and Examples using the esDesign R package
Some associated functions: AED.boundary . AED.sim . AED1_SSR.CP . AED1_SSR.N2 . AED1_SSR.boundary . AED1_SSR.sim . AED2_SSR.CP . AED2_SSR.boundary . AED2_SSR.sim . AED3_SSR.CP . AED3_SSR.boundary . AED3_SSR.sim . MaST.sim . SD.sim . SSR.CP . SSR.boundary . SSR.sim . SigP . sSize.norm . 
Some associated R codes: esDesign.R .  Full esDesign package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

AzureKeyVault  
Key and Secret Management in 'Azure'
Manage keys, certificates, secrets, and storage accounts in Microsoft's 'Key Vault' service: ...
Download / Learn more Package Citations See dependency  
PeakSegOptimal  
Optimal Segmentation Subject to Up-Down Constraints
Computes optimal changepoint models using the Poisson likelihood for non-negative count data, subj ...
Download / Learn more Package Citations See dependency  
r2resize  
In-Text Resize for Images, Tables and Fancy Resize Containers in 'shiny', 'rmarkdown' and 'quarto' Documents
Automatic resizing toolbar for containers, images and tables. Various resizable or expandable contai ...
Download / Learn more Package Citations See dependency  
assert  
Validate Function Arguments
Lightweight validation tool for checking function arguments and validating data analysis scripts. T ...
Download / Learn more Package Citations See dependency  
AHSurv  
Flexible Parametric Accelerated Hazards Models
Flexible parametric Accelerated Hazards (AH) regression models in overall and relative survival fram ...
Download / Learn more Package Citations See dependency  

27,535

R Packages

236,180

Dependencies

73,487

Author Associations

27,536

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA