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dtpcrm
View on CRAN: Click
here
Download and install dtpcrm package within the R console
Install from CRAN:
install.packages("dtpcrm")
Install from Github:
library("remotes")
install_github("cran/dtpcrm") Install by package version:
library("remotes")
install_version("dtpcrm", "0.1.1") Attach the package and use:
library("dtpcrm")
Maintained by
Christina Yap
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2019-04-10
Latest Update: 2019-08-20
Description:
Provides the dose transition pathways (DTP) to project in advance
the doses recommended by a model-based design for subsequent patients (stay,
escalate, deescalate or stop early) using all the accumulated toxicity
information; See Yap et al (2017) . DTP
can be used as a design and an operational tool and can be displayed as a
table or flow diagram. The 'dtpcrm' package also provides the modified
continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with
added practical considerations to allow stopping early when there is
sufficient evidence that the lowest dose is too toxic and/or there is a
sufficient number of patients dosed at the maximum tolerated dose.
How to cite:
Christina Yap (2019). dtpcrm: Dose Transition Pathways for Continual Reassessment Method. R package version 0.1.1, https://cran.r-project.org/web/packages/dtpcrm. Accessed 02 Nov. 2026.
Previous versions and publish date:
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imports, suggests or enhances
Complete documentation for dtpcrm
Functions, R codes and Examples using
the dtpcrm R package
Some associated functions: applied_crm . applied_crm_sim . applied_titecrm . applied_titecrm_sim . applied_titecrmts_sim . calculate_dtps . dtpflow . plot_crm . stop_for_consensus_reached . stop_for_excess_toxicity_empiric . stop_for_excess_toxicity_logistic . stop_for_sample_size . summary_crm .
Some associated R codes: applied_crm.R . applied_titecrm.R . dtps.R . dtps_flow_chart.R . print_mtd.R . simulation.R . simulation_titecrm.R . simulation_titecrmts.R . stopping_delegates.R . Full dtpcrm package functions and examples
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