Other packages > Find by keyword >

crm12Comb  

Phase I/II CRM Based Drug Combination Design
View on CRAN: Click here


Download and install crm12Comb package within the R console
Install from CRAN:
install.packages("crm12Comb")

Install from Github:
library("remotes")
install_github("cran/crm12Comb")

Install by package version:
library("remotes")
install_version("crm12Comb", "0.1.9")



Attach the package and use:
library("crm12Comb")
Maintained by
Junying Wang
[Scholar Profile | Author Map]
First Published: 2024-05-02
Latest Update: 2024-05-02
Description:
Implements the adaptive designs for integrated phase I/II trials of drug combinations via continual reassessment method (CRM) to evaluate toxicity and efficacy simultaneously for each enrolled patient cohort based on Bayesian inference. It supports patients assignment guidance in a single trial using current enrolled data, as well as conducting extensive simulation studies to evaluate operating characteristics before the trial starts. It includes various link functions such as empiric, one-parameter logistic, two-parameter logistic, and hyperbolic tangent, as well as considering multiple prior distributions of the parameters like normal distribution, gamma distribution and exponential distribution to accommodate diverse clinical scenarios. Method using Bayesian framework with empiric link function is described in: Wages and Conaway (2014) <doi:10.1002/sim.6097>.
How to cite:
Junying Wang (2024). crm12Comb: Phase I/II CRM Based Drug Combination Design. R package version 0.1.9, https://cran.r-project.org/web/packages/crm12Comb. Accessed 01 Apr. 2025.
Previous versions and publish date:
0.1.3 (2024-05-02 17:52), 0.1.4 (2024-05-27 00:30), 0.1.5 (2024-06-04 23:00), 0.1.6 (2024-06-07 14:20), 0.1.7 (2024-09-16 16:30), 0.1.8 (2024-11-03 17:50), 0.1.9 (2024-12-10 04:30), 0.1.10 (2025-03-18 11:50)
Other packages that cited crm12Comb R package
View crm12Comb citation profile
Other R packages that crm12Comb depends, imports, suggests or enhances
Complete documentation for crm12Comb
Functions, R codes and Examples using the crm12Comb R package
Full crm12Comb package functions and examples
Downloads during the last 30 days
03/0203/0303/0403/0503/0603/0703/0803/0903/1003/1103/1203/1303/1403/1503/1603/1703/1803/1903/2003/2103/2203/2303/2403/2503/2603/2703/2803/2903/3003/31Downloads for crm12Comb0510152025303540TrendBars

Today's Hot Picks in Authors and Packages

simplevis  
Wrappers to Simplify Beautiful "ggplot2" and "leaflet" Visualisation
Wrapper functions around the amazing 'leaflet' package that aims to simplify 'leaflet' visualisatio ...
Download / Learn more Package Citations See dependency  
quickcode  
Quick and Essential 'R' Tricks for Better Scripts
The NOT functions, 'R' tricks and a compilation of some simple quick plus often used 'R' codes to im ...
Download / Learn more Package Citations See dependency  
gasmodel  
Generalized Autoregressive Score Models
Estimation, forecasting, and simulation of generalized autoregressive score (GAS) models of Creal, ...
Download / Learn more Package Citations See dependency  
samplesize  
Sample Size Calculation for Various t-Tests and Wilcoxon-Test
Computes sample size for Student's t-test and for the Wilcoxon-Mann-Whitney test for categorical dat ...
Download / Learn more Package Citations See dependency  
shinyBS  
Twitter Bootstrap Components for Shiny
Adds additional Twitter Bootstrap components to Shiny. ...
Download / Learn more Package Citations See dependency  
eSIR  
Extended State-Space SIR Models
An implementation of extended state-space SIR models developed by Song Lab at UM school of Public H ...
Download / Learn more Package Citations See dependency  

23,842

R Packages

207,311

Dependencies

64,420

Author Associations

23,781

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA