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cobenrich
View on CRAN: Click
here
Download and install cobenrich package within the R console
Install from CRAN:
install.packages("cobenrich")
Install from Github:
library("remotes")
install_github("cran/cobenrich")
Install by package version:
library("remotes")
install_version("cobenrich", "1.0.1")
Attach the package and use:
library("cobenrich")
Maintained by
Jiangtao Gou
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-04-15
Latest Update: 2025-04-15
Description:
Enrichment strategies play a critical role in modern clinical trial design, especially as precision medicine advances the focus on patient-specific efficacy. Recent developments in enrichment design have introduced biomarker randomness and accounted for the correlation structure between treatment effect and biomarker, resulting in a two-stage threshold enrichment design. We propose novel two-stage enrichment designs capable of handling two or more continuous biomarkers. See Zhang, F. and Gou, J. (2025). Using multiple biomarkers for patient enrichment in two-stage clinical designs. Technical Report.
How to cite:
Jiangtao Gou (2025). cobenrich: Using Multiple Continuous Biomarkers for Patient Enrichment in Two-Stage Clinical Designs. R package version 1.0.1, https://cran.r-project.org/web/packages/cobenrich. Accessed 03 May. 2025.
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