Other packages > Find by keyword >

bbssr  

Blinded Sample Size Re-Estimation for Binary Endpoints
View on CRAN: Click here


Download and install bbssr package within the R console
Install from CRAN:
install.packages("bbssr")

Install from Github:
library("remotes")
install_github("cran/bbssr")

Install by package version:
library("remotes")
install_version("bbssr", "1.0.2")



Attach the package and use:
library("bbssr")
Maintained by
Gosuke Homma
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-06-18
Latest Update: 2025-06-18
Description:
Provides comprehensive tools for blinded sample size re-estimation (BSSR) in two-arm clinical trials with binary endpoints. Unlike traditional fixed-sample designs, BSSR allows adaptive sample size adjustments during trials while maintaining statistical integrity and study blinding. Implements five exact statistical tests: Pearson chi-squared, Fisher exact, Fisher mid-p, Z-pooled exact unconditional, and Boschloo exact unconditional tests. Supports restricted, unrestricted, and weighted BSSR approaches with exact Type I error control. Statistical methods based on Mehrotra et al. (2003) <doi:10.1111/1541-0420.00051> and Kieser (2020) <doi:10.1007/978-3-030-49528-2_21>.
How to cite:
Gosuke Homma (2025). bbssr: Blinded Sample Size Re-Estimation for Binary Endpoints. R package version 1.0.2, https://cran.r-project.org/web/packages/bbssr. Accessed 10 Mar. 2026.
Previous versions and publish date:
No previous versions
Other packages that cited bbssr R package
View bbssr citation profile
Other R packages that bbssr depends, imports, suggests or enhances
Complete documentation for bbssr
Functions, R codes and Examples using the bbssr R package
Full bbssr package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

envirem  
Generation of ENVIREM Variables
Generation of bioclimatic rasters that are complementary to the typical 19 bioclim variables. ...
Download / Learn more Package Citations See dependency  
plyr  
Tools for Splitting, Applying and Combining Data
A set of tools that solves a common set of problems: you need to break a big problem down into mana ...
Download / Learn more Package Citations See dependency  
nextGenShinyApps  
Craft Exceptional 'R Shiny' Applications and Dashboards with Novel Responsive Tools
Nove responsive tools for designing and developing 'Shiny' dashboards and applications. The scripts ...
Download / Learn more Package Citations See dependency  
gena  
Genetic Algorithm and Particle Swarm Optimization
Implements genetic algorithm and particle swarm algorithm for real-valued functions. Various modific ...
Download / Learn more Package Citations See dependency  

26,293

R Packages

225,784

Dependencies

70,376

Author Associations

26,294

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA