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ZetaSuite  

Analyze High-Dimensional High-Throughput Dataset and Quality Control Single-Cell RNA-Seq
View on CRAN: Click here


Download and install ZetaSuite package within the R console
Install from CRAN:
install.packages("ZetaSuite")

Install from Github:
library("remotes")
install_github("cran/ZetaSuite")

Install by package version:
library("remotes")
install_version("ZetaSuite", "1.0.1")



Attach the package and use:
library("ZetaSuite")
Maintained by
Junhui Li
[Scholar Profile | Author Map]
First Published: 2022-03-31
Latest Update: 2022-05-24
Description:
The advent of genomic technologies has enabled the generation of two-dimensional or even multi-dimensional high-throughput data, e.g., monitoring multiple changes in gene expression in genome-wide siRNA screens across many different cell types (E Robert McDonald 3rd (2017) <doi:10.1016/j.cell.2017.07.005> and Tsherniak A (2017) <doi:10.1016/j.cell.2017.06.010>) or single cell transcriptomics under different experimental conditions. We found that simple computational methods based on a single statistical criterion is no longer adequate for analyzing such multi-dimensional data. We herein introduce 'ZetaSuite', a statistical package initially designed to score hits from two-dimensional RNAi screens.We also illustrate a unique utility of 'ZetaSuite' in analyzing single cell transcriptomics to differentiate rare cells from damaged ones (Vento-Tormo R (2018) <doi:10.1038/s41586-018-0698-6>). In 'ZetaSuite', wehave the following steps: QC of input datasets, normalization using Z-transformation, Zeta score calculation and hits selection based on defined Screen Strength.
How to cite:
Junhui Li (2022). ZetaSuite: Analyze High-Dimensional High-Throughput Dataset and Quality Control Single-Cell RNA-Seq. R package version 1.0.1, https://cran.r-project.org/web/packages/ZetaSuite. Accessed 19 Feb. 2025.
Previous versions and publish date:
1.0.0 (2022-03-31 09:30)
Other packages that cited ZetaSuite R package
View ZetaSuite citation profile
Other R packages that ZetaSuite depends, imports, suggests or enhances
Complete documentation for ZetaSuite
Functions, R codes and Examples using the ZetaSuite R package
Some associated functions: EventCoverage . FDRcutoff . QC . SVM . SVMcurve . Zeta . ZetaSuitSC . Zscore . ZseqList . countMat . countMatSC . negGene . nonExpGene . posGene . 
Some associated R codes: EventCoverage.R . FDRcutoff.R . QC.R . SVM.R . Zeta.R . ZetaSuitSC.R . Zscore.R .  Full ZetaSuite package functions and examples
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