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TwoDiRef
View on CRAN: Click
here
Download and install TwoDiRef package within the R console
Install from CRAN:
install.packages("TwoDiRef")
Install from Github:
library("remotes")
install_github("cran/TwoDiRef") Install by package version:
library("remotes")
install_version("TwoDiRef", "0.1.0") Attach the package and use:
library("TwoDiRef")
Maintained by
Oscar Lado-Baleato
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[Scholar Profile | Author Map]
All associated links for this package
First Published: 2026-03-30
Latest Update: 2026-03-30
Description:
Provides tools for constructing conditional two-dimensional reference regions in continuous data, particularly suited for clinical, biological, or epidemiological studies requiring robust multivariate assessment. The implemented methodology combines directional quantiles with median‑based partial correlation models to produce reliable and interpretable reference regions even in the presence of outliers. Key features include robust conditional modeling for two responses conditioned on covariates, directional quantile regions, cross‑validation of coverage, visualization tools, and flexible formula‑based inputs.
How to cite:
Oscar Lado-Baleato (2026). TwoDiRef: Robust Estimation of Conditional 2D Reference Regions. R package version 0.1.0, https://cran.r-project.org/web/packages/TwoDiRef. Accessed 28 Jul. 2026.
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