Other packages > Find by keyword >

TTCA  

Transcript Time Course Analysis
View on CRAN: Click here


Download and install TTCA package within the R console
Install from CRAN:
install.packages("TTCA")

Install from Github:
library("remotes")
install_github("cran/TTCA")

Install by package version:
library("remotes")
install_version("TTCA", "0.1.1")



Attach the package and use:
library("TTCA")
Maintained by
Marco Albrecht
[Scholar Profile | Author Map]
First Published: 2016-06-20
Latest Update: 2017-01-29
Description:
The analysis of microarray time series promises a deeper insight into the dynamics of the cellular response following stimulation. A common observation in this type of data is that some genes respond with quick, transient dynamics, while other genes change their expression slowly over time. The existing methods for detecting significant expression dynamics often fail when the expression dynamics show a large heterogeneity. Moreover, these methods often cannot cope with irregular and sparse measurements. The method proposed here is specifically designed for the analysis of perturbation responses. It combines different scores to capture fast and transient dynamics as well as slow expression changes, and performs well in the presence of low replicate numbers and irregular sampling times. The results are given in the form of tables including links to figures showing the expression dynamics of the respective transcript. These allow to quickly recognise the relevance of detection, to identify possible false positives and to discriminate early and late changes in gene expression. An extension of the method allows the analysis of the expression dynamics of functional groups of genes, providing a quick overview of the cellular response. The performance of this package was tested on microarray data derived from lung cancer cells stimulated with epidermal growth factor (EGF). Paper: Albrecht, Marco, et al. (2017)<doi:10.1186/s12859-016-1440-8>.
How to cite:
Marco Albrecht (2016). TTCA: Transcript Time Course Analysis. R package version 0.1.1, https://cran.r-project.org/web/packages/TTCA. Accessed 07 May. 2025.
Previous versions and publish date:
0.1.0 (2016-06-20 08:19)
Other packages that cited TTCA R package
View TTCA citation profile
Other R packages that TTCA depends, imports, suggests or enhances
Complete documentation for TTCA
Functions, R codes and Examples using the TTCA R package
Some associated functions: Control . EGF . TTCA . annot . annotation . 
Some associated R codes: TTCA.R .  Full TTCA package functions and examples
Downloads during the last 30 days
04/0704/0804/0904/1004/1104/1204/1304/1404/1504/1604/1704/1804/1904/2004/2104/2204/2304/2404/2504/2604/2704/2804/2904/3005/0205/0305/0405/0505/06Downloads for TTCA0246810121416182022242628TrendBars

Today's Hot Picks in Authors and Packages

funLBM  
Model-Based Co-Clustering of Functional Data
The funLBM algorithm allows to simultaneously cluster the rows and the columns of a data matrix wher ...
Download / Learn more Package Citations See dependency  
MLDS  
Maximum Likelihood Difference Scaling
Difference scaling is a method for scaling perceived supra-threshold differences. The package cont ...
Download / Learn more Package Citations See dependency  
quickcode  
Quick and Essential 'R' Tricks for Better Scripts
The NOT functions, 'R' tricks and a compilation of some simple quick plus often used 'R' codes to im ...
Download / Learn more Package Citations See dependency  
aroma.affymetrix  
Analysis of Large Affymetrix Microarray Data Sets
A cross-platform R framework that facilitates processing of any number of Affymetrix microarray samp ...
Download / Learn more Package Citations See dependency  
humanize  
Create Values for Human Consumption
An almost direct port of the 'python' 'humanize' package . Thi ...
Download / Learn more Package Citations See dependency  

24,205

R Packages

207,311

Dependencies

65,312

Author Associations

24,206

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA