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SubtypeDrug  

Prioritization of Candidate Cancer Subtype Specific Drugs
View on CRAN: Click here


Download and install SubtypeDrug package within the R console
Install from CRAN:
install.packages("SubtypeDrug")

Install from Github:
library("remotes")
install_github("cran/SubtypeDrug")

Install by package version:
library("remotes")
install_version("SubtypeDrug", "0.1.9")



Attach the package and use:
library("SubtypeDrug")
Maintained by
Junwei Han
[Scholar Profile | Author Map]
First Published: 2020-05-16
Latest Update: 2024-01-21
Description:
A systematic biology tool was developed to prioritize cancer subtype-specific drugs by integrating genetic perturbation, drug action, biological pathway, and cancer subtype. The capabilities of this tool include inferring patient-specific subpathway activity profiles in the context of gene expression profiles with subtype labels, calculating differentially expressed subpathways based on cultured human cells treated with drugs in the 'cMap' (connectivity map) database, prioritizing cancer subtype specific drugs according to drug-disease reverse association score based on subpathway, and visualization of results (Castelo (2013) <doi:10.1186/1471-2105-14-7>; Han et al (2019) <doi:10.1093/bioinformatics/btz894>; Lamb and Justin (2006) <doi:10.1126/science.1132939>). Please cite using <doi:10.1093/bioinformatics/btab011>.
How to cite:
Junwei Han (2020). SubtypeDrug: Prioritization of Candidate Cancer Subtype Specific Drugs. R package version 0.1.9, https://cran.r-project.org/web/packages/SubtypeDrug. Accessed 30 Apr. 2025.
Previous versions and publish date:
0.1.0 (2020-05-16 11:30), 0.1.1 (2020-06-26 06:50), 0.1.2 (2020-09-24 13:00), 0.1.3 (2020-11-24 09:30), 0.1.4 (2021-01-22 10:00), 0.1.5 (2021-05-17 10:50), 0.1.6 (2024-01-10 15:23), 0.1.7 (2024-01-21 16:32), 0.1.8 (2024-03-18 07:00)
Other packages that cited SubtypeDrug R package
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Complete documentation for SubtypeDrug
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