Other packages > Find by keyword >

SQUIRE  

Statistical Quality-Assured Integrated Response Estimation
View on CRAN: Click here


Download and install SQUIRE package within the R console
Install from CRAN:
install.packages("SQUIRE")

Install from Github:
library("remotes")
install_github("cran/SQUIRE")

Install by package version:
library("remotes")
install_version("SQUIRE", "1.0.1")



Attach the package and use:
library("SQUIRE")
Maintained by
Richard A. Feiss
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-11-19
Latest Update: 2025-11-19
Description:
Implements statistically validated biological parameter optimization that combines automated parameter type detection with rigorous statistical quality assurance. Unlike conventional optimizers that fit parameters to any data, 'SQUIRE' first validates whether statistically significant biological effects exist before proceeding with parameter estimation. Uses trust region methods from Conn et al. (2000) <doi:10.1137/S1052623497325107>, ANOVA-based validation following Fisher (1925) <doi:10.1007/978-1-4612-4380-9_6>, and effect size calculations per Cohen (1988, ISBN:0805802835). Automatically distinguishes rate-based, positive-constrained, and unconstrained variables, applying geometry-appropriate optimization methods while preventing over-fitting to noise through built-in statistical validation, effect size assessment, and data quality requirements. Designed for complex biological and environmental models including germination studies, dose-response curves, and survival analysis. Enhanced successor to the 'GALAHAD' optimization framework with integrated statistical gatekeeping. Developed at the Minnesota Center for Prion Research and Outreach at the University of Minnesota.
How to cite:
Richard A. Feiss (2025). SQUIRE: Statistical Quality-Assured Integrated Response Estimation. R package version 1.0.1, https://cran.r-project.org/web/packages/SQUIRE. Accessed 05 Jun. 2026.
Previous versions and publish date:
1.0.0 (2025-11-19 19:00), 1.0.1 (2025-12-01 00:40)
Other packages that cited SQUIRE R package
View SQUIRE citation profile
Other R packages that SQUIRE depends, imports, suggests or enhances
Complete documentation for SQUIRE
Functions, R codes and Examples using the SQUIRE R package
Full SQUIRE package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

envirem  
Generation of ENVIREM Variables
Generation of bioclimatic rasters that are complementary to the typical 19 bioclim variables. ...
Download / Learn more Package Citations See dependency  
msm  
Multi-State Markov and Hidden Markov Models in Continuous Time
Functions for fitting continuous-time Markov and hidden Markov multi-state models to longitudinal d ...
Download / Learn more Package Citations See dependency  
ibb  
R Wrapper for Istanbul Municipality Open Data Portal
Call wrappers for Istanbul Metropolitan Municipality's Open Data Portal (Turkish: Istanbul B ...
Download / Learn more Package Citations See dependency  
quickcode  
Quick and Essential 'R' Tricks for Better Scripts
The NOT functions, 'R' tricks and a compilation of some simple quick plus often used 'R' codes to im ...
Download / Learn more Package Citations See dependency  
crossurr  
Cross-Fitting for Doubly Robust Evaluation of High-Dimensional Surrogate Markers
Doubly robust methods for evaluating surrogate markers as outlined in: Agniel D, Hejblum BP, Thiebau ...
Download / Learn more Package Citations See dependency  

27,268

R Packages

233,548

Dependencies

72,590

Author Associations

27,205

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA