Other packages > Find by keyword >

SEAGLE  

Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests
View on CRAN: Click here


Download and install SEAGLE package within the R console
Install from CRAN:
install.packages("SEAGLE")

Install from Github:
library("remotes")
install_github("cran/SEAGLE")

Install by package version:
library("remotes")
install_version("SEAGLE", "1.0.1")



Attach the package and use:
library("SEAGLE")
Maintained by
Jocelyn Chi
[Scholar Profile | Author Map]
First Published: 2021-06-07
Latest Update: 2021-11-05
Description:
The explosion of biobank data offers immediate opportunities for gene-environment (GxE) interaction studies of complex diseases because of the large sample sizes and rich collection in genetic and non-genetic information. However, the extremely large sample size also introduces new computational challenges in GxE assessment, especially for set-based GxE variance component (VC) tests, a widely used strategy to boost overall GxE signals and to evaluate the joint GxE effect of multiple variants from a biologically meaningful unit (e.g., gene). We present 'SEAGLE', a Scalable Exact AlGorithm for Large-scale Set-based GxE tests, to permit GxE VC test scalable to biobank data. 'SEAGLE' employs modern matrix computations to achieve the same
How to cite:
Jocelyn Chi (2021). SEAGLE: Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests. R package version 1.0.1, https://cran.r-project.org/web/packages/SEAGLE. Accessed 31 Mar. 2025.
Previous versions and publish date:
1.0.0 (2021-06-07 09:10)
Other packages that cited SEAGLE R package
View SEAGLE citation profile
Other R packages that SEAGLE depends, imports, suggests or enhances
Complete documentation for SEAGLE
Functions, R codes and Examples using the SEAGLE R package
Some associated functions: Rinv.AtG . Rinv.u . SEAGLE . Vinv . applyAt . cosihap . estimate.vc . makeSimData . prep.SEAGLE . 
Some associated R codes: data.R . em_reml.R . makeData.R . prepData.R . score.R .  Full SEAGLE package functions and examples
Downloads during the last 30 days
03/0103/0203/0303/0403/0503/0603/0703/0803/0903/1003/1103/1203/1303/1403/1503/1603/1803/1903/2003/2103/2203/2303/2403/2503/2603/2703/28Downloads for SEAGLE0246810121416TrendBars

Today's Hot Picks in Authors and Packages

tclust  
Robust Trimmed Clustering
Provides functions for robust trimmed clustering. The methods are described in Garcia-Escudero (200 ...
Download / Learn more Package Citations See dependency  
surveillance  
Temporal and Spatio-Temporal Modeling and Monitoring of Epidemic Phenomena
Statistical methods for the modeling and monitoring of time series of counts, proportions and catego ...
Download / Learn more Package Citations See dependency  
popbio  
Construction and Analysis of Matrix Population Models
Construct and analyze projection matrix models from a demography study of marked individuals classif ...
Download / Learn more Package Citations See dependency  
PermutationR  
Conduct Permutation Analysis of Variance in R
Conduct permutation One-Way or Two-Way Analysis of Variance in R. Use different permutation types fo ...
Download / Learn more Package Citations See dependency  
whitebox  
'WhiteboxTools' R Frontend
An R frontend for the 'WhiteboxTools' library, which is an advanced geospatial data analysis platfor ...
Download / Learn more Package Citations See dependency  
bodycomp  
Percent Body Fat Values Using Anthropometric Prediction Equations
Skinfold measurements is one of the most popular and practical methods for estimating percent body f ...
Download / Learn more Package Citations See dependency  

23,842

R Packages

207,311

Dependencies

64,420

Author Associations

23,781

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA