Other packages > Find by keyword >

RestoreNet  

Random-Effects Stochastic Reaction Networks
View on CRAN: Click here


Download and install RestoreNet package within the R console
Install from CRAN:
install.packages("RestoreNet")

Install from Github:
library("remotes")
install_github("cran/RestoreNet")

Install by package version:
library("remotes")
install_version("RestoreNet", "1.0.1")



Attach the package and use:
library("RestoreNet")
Maintained by
Luca Del Core
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2022-09-20
Latest Update: 2024-02-15
Description:
A random-effects stochastic model that allows quick detection of clonal dominance events from clonal tracking data collected in gene therapy studies. Starting from the Ito-type equation describing the dynamics of cells duplication, death and differentiation at clonal level, we first considered its local linear approximation as the base model. The parameters of the base model, which are inferred using a maximum likelihood approach, are assumed to be shared across the clones. Although this assumption makes inference easier, in some cases it can be too restrictive and does not take into account possible scenarios of clonal dominance. Therefore we extended the base model by introducing random effects for the clones. In this extended formulation the dynamic parameters are estimated using a tailor-made expectation maximization algorithm. Further details on the methods can be found in L. Del Core et al., (2022) .
How to cite:
Luca Del Core (2022). RestoreNet: Random-Effects Stochastic Reaction Networks. R package version 1.0.1, https://cran.r-project.org/web/packages/RestoreNet. Accessed 28 Oct. 2026.
Previous versions and publish date:
(2026-07-09 08:23), 1.0 (2022-09-20 12:46)
Other packages that cited RestoreNet R package
View RestoreNet citation profile
Other R packages that RestoreNet depends, imports, suggests or enhances
Complete documentation for RestoreNet
Functions, R codes and Examples using the RestoreNet R package
Some associated functions: BhattDist . KLDiv . VEuy . Y_RM . compile.h . condAIC . dBu . dD2 . dmvNorm . fit.null . fit.re . get.M . get.V . get.W . get.boxplots . get.dx . get.gnl . get.nl . get.rescaled . get.scatterpie . get.sim.tl . ldet . nQ . ngQ . norm2 . nullModelFitting . ny_u . relErr . rmvNorm . rndEffModelFitting . rndEffModelStats . tr . 
Some associated R codes: data.R . functions.R . importPackages.R .  Full RestoreNet package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

NPHazardRate  
Nonparametric Hazard Rate Estimation
Provides functions and examples for histogram, kernel (classical, variable bandwidth and transformat ...
Download / Learn more Package Citations See dependency  
msamp  
Estimate Sample Size to Detect Bacterial Contamination in a Product Lot
Estimates the sample size needed to detect microbial contamination in a lot with a user-specified d ...
Download / Learn more Package Citations See dependency  
nextGenShinyApps  
Craft Exceptional 'R Shiny' Applications and Dashboards with Novel Responsive Tools
Nove responsive tools for designing and developing 'Shiny' dashboards and applications. The scripts ...
Download / Learn more Package Citations See dependency  
cats  
Cohort Platform Trial Simulation
Cohort plAtform Trial Simulation whereby every cohort consists of two arms, control and experimenta ...
Download / Learn more Package Citations See dependency  
ncdf4  
Interface to Unidata netCDF (Version 4 or Earlier) Format Data Files
Provides a high-level R interface to data files written using Unidata's netCDF library (version 4 or ...
Download / Learn more Package Citations See dependency  

29,218

R Packages

247,686

Dependencies

77,281

Author Associations

29,219

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA