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RPPASPACE  

Reverse-Phase Protein Array Super Position and Concentration Evaluation
View on CRAN: Click here


Download and install RPPASPACE package within the R console
Install from CRAN:
install.packages("RPPASPACE")

Install from Github:
library("remotes")
install_github("cran/RPPASPACE")

Install by package version:
library("remotes")
install_version("RPPASPACE", "1.0.10")



Attach the package and use:
library("RPPASPACE")
Maintained by
James M. Melott
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2020-12-10
Latest Update: 2023-10-19
Description:
Provides tools for the analysis of reverse-phase protein arrays (RPPAs), which are also known as 'tissue lysate arrays' or simply 'lysate arrays'. The package's primary purpose is to input a set of quantification files representing dilution series of samples and control points taken from scanned RPPA slides and determine a relative log concentration value for each valid dilution series present in each slide and provide graphical visualization of the input and output data and their relationships. Other optional features include generation of quality control scores for judging the quality of the input data, spatial adjustment of sample points based on controls added to the slides, and various types of normalization of calculated values across a set of slides. The package was derived from a previous package named SuperCurve. For a detailed description of data inputs and outputs, usage information, and a list of related papers describing methods used in the package please review the vignette 'Guide_to_RPPASPACE'. 'RPPA SPACE: an R package for normalization and quantitation of Reverse-Phase Protein Array data'. Bioinformatics Nov 15;38(22):5131-5133. .
How to cite:
James M. Melott (2020). RPPASPACE: Reverse-Phase Protein Array Super Position and Concentration Evaluation. R package version 1.0.10, https://cran.r-project.org/web/packages/RPPASPACE. Accessed 05 Mar. 2026.
Previous versions and publish date:
1.0.7 (2020-12-10 16:50), 1.0.8 (2021-10-20 19:40), 1.0.9 (2023-08-18 16:52)
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Complete documentation for RPPASPACE
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