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PopED  

Population (and Individual) Optimal Experimental Design
View on CRAN: Click here


Download and install PopED package within the R console
Install from CRAN:
install.packages("PopED")

Install from Github:
library("remotes")
install_github("cran/PopED")

Install by package version:
library("remotes")
install_version("PopED", "0.7.0")



Attach the package and use:
library("PopED")
Maintained by
Andrew C. Hooker
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2014-04-28
Latest Update: 2024-10-07
Description:
Optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix. This package was developed for pharmacometric problems, and examples and predefined models are available for these types of systems. The methods are described in Nyberg et al. (2012) , and Foracchia et al. (2004) .
How to cite:
Andrew C. Hooker (2014). PopED: Population (and Individual) Optimal Experimental Design. R package version 0.7.0, https://cran.r-project.org/web/packages/PopED. Accessed 28 Oct. 2026.
Previous versions and publish date:
(2026-07-09 08:17), 0.1.0 (2014-04-28 11:08), 0.1.1 (2014-05-27 15:44), 0.1.2 (2014-11-19 14:03), 0.2.0 (2015-03-20 18:04), 0.3.0 (2015-12-29 22:29), 0.3.1 (2016-10-19 13:07), 0.3.2 (2016-12-12 18:16), 0.4.0 (2018-09-10 11:40), 0.5.0 (2020-06-13 16:50), 0.6.0 (2021-05-21 16:50)
Other packages that cited PopED R package
View PopED citation profile
Other R packages that PopED depends, imports, suggests or enhances
Complete documentation for PopED
Functions, R codes and Examples using the PopED R package
Some associated functions: Doptim . Dtrace . LEDoptim . LinMatrixH . LinMatrixL . LinMatrixLH . LinMatrixL_occ . PopED . RS_opt . a_line_search . bfgsb_min . blockexp . blockfinal . blockheader . blockopt . build_sfg . calc_autofocus . calc_ofv_and_fim . calc_ofv_and_grad . cell . convert_variables . create.poped.database . create_design . create_design_space . design_summary . diag_matlab . downsizing_general_design . ed_laplace_ofv . ed_mftot . efficiency . evaluate.e.ofv.fim . evaluate.fim . evaluate_design . evaluate_fim_map . evaluate_power . extract_norm_group_fim . feps.add . feps.add.prop . feps.prop . feval . ff.PK.1.comp.oral.md.CL . ff.PK.1.comp.oral.md.KE . ff.PK.1.comp.oral.sd.CL . ff.PK.1.comp.oral.sd.KE . ff.PKPD.1.comp.oral.md.CL.imax . ff.PKPD.1.comp.sd.CL.emax . fileparts . getTruncatedNormal . get_all_params . get_rse . get_unfixed_params . getfulld . gradf_eps . inv . isempty . log_prior_pdf . mc_mean . median_hilow_poped . mf3 . mf7 . mfea . mftot . model_prediction . ofv_criterion . ofv_fim . ones . optim_ARS . optim_LS . optimize_groupsize . optimize_n_eff . optimize_n_rse . pargen . plot_efficiency_of_windows . plot_model_prediction . poped.choose . poped_gui . poped_optim . poped_optim_1 . poped_optim_2 . poped_optim_3 . poped_optimize . rand . randn . shrinkage . size . start_parallel . summary.poped_optim . test_mat_size . tic . toc . tryCatch.W.E . zeros . 
Some associated R codes: Doptim.R . Dtrace.R . LEDoptim.R . LinMatrixH.R . LinMatrixL.R . LinMatrixLH.R . LinMatrixL_occ.R . PopED.R . RS_opt.R . a_line_search.R . add_to_poped_db.R . bfgsb_min.R . blockexp.R . blockfinal.R . blockheader.R . blockopt.R . blockoptwrt.R . blockother.R . build_sfg.R . calc_ofv_and_fim.R . cauchy_point.R . cell.R . convert_variables.R . create.poped.database.R . create_design.R . create_design_space.R . create_ofv.R . d2fimdalpha2.R . design_summary.R . dfimdalpha.R . diag_matlab.R . downsizing_general_design.R . ed_laplace_ofv.R . ed_mftot.R . efficiency.R . evaluate.e.ofv.fim.R . evaluate.fim.R . evaluate_design.R . evaluate_fim_map.R . evaluate_power.R . feval.R . fileparts.R . find.largest.index.R . fprintf.R . getTruncatedNormal.R . get_all_params.R . get_cv.R . get_discrete_x.R . get_fim_size.R . get_unfixed_params.R . getfulld.R . grad_all.R . grad_bpop.R . graddetmf.R . graddetmf_ext.R . gradff.R . gradfg.R . gradfg_occ.R . gradofv_a.R . gradofv_xt.R . gradtrmf.R . grouped_rand.R . grouped_rand_a.R . helper.R . hessian_eta_complex.R . hesskalpha2.R . ind_estimates.R . ind_likelihood.R . inv.R . isempty.R . line_search.R . line_search_uc.R . linspace.R . log_prior_pdf.R . m1.R . m2.R . m3.R . mc_mean.R . median_hilow_poped.R . mf3.R . mf7.R . mf_all.R . mf_all_loq.R . mfea.R . mftot.R . model_prediction.R . models.R . numel.R . ofv_criterion.R . ofv_fim.R . ofv_optim.R . ones.R . optim_ARS.R . optim_LS.R . optimize_n.R . par_and_space_tbl.R . pargen.R . plot_efficiency_of_windows.R . plot_model_prediction.R . poped_gui.R . poped_optim.R . poped_optim_1.R . poped_optim_2.R . poped_optim_3.R . poped_optimize.R . rand.R . randn.R . shrinkage.R . size.R . start_parallel.R . subspace_min.R . summary.poped_optim.R . test_mat_size.R . tic.R . toc.R . trace_matrix.R . update_designinlist.R . update_offdiag.R . v.R . write_iterationfile.R . write_matrix.R . zeros.R . zzz.R .  Full PopED package functions and examples
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