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Phase123  

Simulating and Conducting Phase 123 Trials
View on CRAN: Click here


Download and install Phase123 package within the R console
Install from CRAN:
install.packages("Phase123")

Install from Github:
library("remotes")
install_github("cran/Phase123")

Install by package version:
library("remotes")
install_version("Phase123", "2.1")



Attach the package and use:
library("Phase123")
Maintained by
Andrew G Chapple
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2018-02-07
Latest Update: 2019-04-25
Description:
Contains three simulation functions for implementing the entire Phase 123 trial and the separate Eff-Tox and Phase 3 portions of the trial, which may be beneficial for use on clusters. The functions AssignEffTox() and RandomizeEffTox() assign doses to patient cohorts during phase 12 and Reoptimize() determines the optimal dose to continue with during Phase 3. The functions ReturnMeansAgent() and ReturnMeanControl() gives the true mean survival for the agent doses and control and ReturnOCS() gives the operating characteristics of the design.
How to cite:
Andrew G Chapple (2018). Phase123: Simulating and Conducting Phase 123 Trials. R package version 2.1, https://cran.r-project.org/web/packages/Phase123. Accessed 05 Oct. 2026.
Previous versions and publish date:
(2026-07-09 08:17), 1.2 (2018-02-07 14:02), 1.4 (2018-02-18 19:12), 1.5 (2018-03-29 00:59), 1.7 (2018-10-12 18:50), 1.8 (2018-10-26 19:50), 1.9 (2018-11-06 16:50), 2.0 (2018-11-09 15:30), 2.1 (2019-04-25 19:50)
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