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PLEXI
View on CRAN: Click
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Download and install PLEXI package within the R console
Install from CRAN:
install.packages("PLEXI")
Install from Github:
library("remotes")
install_github("cran/PLEXI")
Install by package version:
library("remotes")
install_version("PLEXI", "1.0.0")
Attach the package and use:
library("PLEXI")
Maintained by
Behnam Yousefi
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[Scholar Profile | Author Map]
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First Published: 2023-08-09
Latest Update: 2023-08-09
Description:
Interactions between different biological entities are crucial for the function of biological systems.
In such networks, nodes represent biological elements, such as genes, proteins and microbes, and their interactions can be defined by edges, which can be either binary or weighted.
The dysregulation of these networks can be associated with different clinical conditions such as diseases and response to treatments.
However, such variations often occur locally and do not concern the whole network.
To capture local variations of such networks, we propose multiplex network differential analysis (MNDA).
MNDA allows to quantify the variations in the local neighborhood of each node (e.g. gene) between the two given clinical states, and to test for statistical significance of such variation.
Yousefi et al. (2023) .
How to cite:
Behnam Yousefi (2023). PLEXI: Multiplex Network Analysis. R package version 1.0.0, https://cran.r-project.org/web/packages/PLEXI. Accessed 07 Nov. 2024.
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