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PFIM  

Population Fisher Information Matrix
View on CRAN: Click here


Download and install PFIM package within the R console
Install from CRAN:
install.packages("PFIM")

Install from Github:
library("remotes")
install_github("cran/PFIM")

Install by package version:
library("remotes")
install_version("PFIM", "6.1")



Attach the package and use:
library("PFIM")
Maintained by
Romain Leroux
[Scholar Profile | Author Map]
First Published: 2022-06-24
Latest Update: 2023-11-24
Description:
Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentr
How to cite:
Romain Leroux (2022). PFIM: Population Fisher Information Matrix. R package version 6.1, https://cran.r-project.org/web/packages/PFIM. Accessed 04 Apr. 2025.
Previous versions and publish date:
5.0 (2022-06-24 10:10), 6.0.1 (2023-11-20 17:00), 6.0.2 (2023-11-24 12:50), 6.0.3 (2024-03-23 15:30), 6.0 (2023-11-08 01:00)
Other packages that cited PFIM R package
View PFIM citation profile
Other R packages that PFIM depends, imports, suggests or enhances
Complete documentation for PFIM
Functions, R codes and Examples using the PFIM R package
Some associated functions: AdjustLogNormalDistribution . AdjustNormalDistribution . Administration-class . AdministrationConstraint-class . AllowedDoses . Arm-class . BayesianFim-class . CalculatedResidualVariance . Combinaison . Combined1-class . Combined1c-class . Combined2-class . Combined2c-class . Constant-class . Constraint-class . ContinuousConstraint-class . Design-class . DesignConstraint-class . DiscreteConstraint-class . Distribution-class . Evaluate . EvaluateBayesianFIM . EvaluateDesign . EvaluateDesignForEachArm . EvaluateErrorModelDerivatives . EvaluateFIMsAndDesigns . EvaluateIndividualFIM . EvaluateModel . EvaluateModelInfusion . EvaluateModelODE . EvaluateModelODEInfusion . EvaluateODEErrorModelDerivatives . EvaluatePopulationFIM . EvaluateStatisticalModel . EvaluationModel . FedorovWynnAlgorithm-class . FedorovWynnAlgorithm_Rcpp . FillLibraryOfModels . Fim-class . FinalizeFIMForOneElementaryDesign . FixTimeValues . IndividualFIMEvaluateVariance . IndividualFim-class . LibraryOfModels-class . LogNormalDistribution-class . Model-class . ModelEquations-class . ModelError-class . ModelInfusionEquations-class . ModelInfusionODEquations-class . ModelODEquations-class . ModelParameter-class . ModelVariable-class . MultiplicativeAlgorithm-class . MultiplicativeAlgorithm_Rcpp . NormalDistribution-class . Optimization-class . Optimize . OptimizeDesign . PDModel-class . PFIM-package . PFIMProject-class . PFIMProjectReportEvaluation . PFIMProjectReportOptimization . PGBOAlgorithm-class . PKModel-class . PKPDModel-class . PSOAlgorithm-class . PopulationFIMEvaluateVariance . PopulationFim-class . PrepareFIMs . Proportional-class . ProportionalC-class . ReportAndPlots-class . Response-class . SamplingConstraint-class . SamplingTimes-class . SimplexAlgorithm-class . StandardDistribution-class . StatisticalModel-class . addAdministration . addAdministrationConstraint . addArm . addArms . addDesign . addDesignConstraints . addDesigns . addModel . addResponse . addResponses . addSampling . addSamplingConstraint . addSamplingConstraints . addSamplings . allowedContinuousSamplingTimes . allowedDiscretSamplingTimes . changeVariablePKModel . checkParameterInEquations . convertAnalyticToODE . defineCorrelation . defineModelEquations . defineParameter . defineParameters . defineStatisticalModel . defineVariable . defineVariables . fisher.simplex . fixedDoses . fun.amoeba . g . getAdministration . getAdministrationByOutcome . getAdministrationConstraint . getAllowedDose . getAllowedDoses . getAllowedTime . getAllowedTinf . getAmountDose . getAmountOfArms . getArmSize . getArms . getCError . getCondInit . getConditionNumberMatrix . getContentsLibraryOfModels . getCorr . getDVSigma . getDcriterion . getDerivate . getDerivatesAdjustedByDistribution . getDerivatives . getDescription . getDesign . getDeterminant . getDiscret . getDistribution . getDoseOptimisability . getEigenValue . getElementaryProtocols . getEquation . getEquations . getEquationsModel . getEquationsModelPKPD . getEquationsStatisticalModel . getErrorModelParameters . getErrorModelStandardErrors . getEvaluationDesign . getEvaluationResponses . getFim . getFimOfDesign . getFims . getFisherMatrices . getFixedParameters . getInfusionEquations . getInitialTime . getMfisher . getModel . getModelError . getModelName . getModelNameList . getModelParameters . getMu . getNameAdministration . getNameArm . getNameDesign . getNameDesignConstraint . getNameModelParameter . getNameModelVariable . getNamePFIMProject . getNameResponse . getNameSampleTime . getNumberOfDoses . getNumberOfParameter . getNumberOfParameters . getNumberOfSamplings . getNumberSamples . getNumberTime . getOmega . getOptimalDesign . getOptimisability . getOptimizationResult . getPDModel . getPKModel . getPKPDModel . getParameters . getParametersOdeSolver . getRange . getResponseIndice . getResponseName . getResponseNameByIndice . getResponsesStatisticalModel . getSE . getSampleTime . getSamplingConstraints . getSamplingConstraintsInArm . getSamplings . getShrinkage . getSig . getSigmaInter . getSigmaNames . getSigmaSlope . getSigmaValues . getStatisticalModel . getStatisticalModelStandardErrors . getTau . getTimeDose . getTinf . getTotalNumberOfIndividuals . getTotalSize . getWeightFrame . getWeights . getallowedContinuousSamplingTimes . getallowedDiscretSamplingTimes . getfixedTimes . getnumberOfSamplingTimes . is.multidose . isFixed . isFixedMu . isLessThanDelay . isNotFixed . isNotFixedMu . isTimeInBetweenBounds . knitrAdministrationParameters . knitrFIM . knitrInitialDesigns . knitrModelEquations . knitrModelError . knitrModelParameters . knitrOptimalDesign . modifyArm . modifySamplingTimes . numberOfSamplingTimesIsOptimisable . parametersForComputingGradient . plotCriteria . plotFrequenciesOptimisation . plotRSE . plotResponse . plotSE . plotSensitivity . plotShrinkage . plotWeightOptimisation . remplaceDose . reportPFIMProject . resizeFisherMatrix . scaleResponsesEvaluationODE . scaleResponsesEvaluationODEInfusion . setAllowedDose-set . setAllowedTime-set . setAllowedTinf-set . setAmountDose . setAmountOfArms . setAmountOfArmsAim . setArmSize . setArms . setCError-set . setConstraint . setDelta . setDesign . setDiscret-set . setInitialConditions . setIteration . setMfisher-set . setModelError-set . setMu . setNameDesign . setNamePFIMProject . setNumberSamples-set . setOmega . setOptimalDesign-set . setParametersForEvaluateModel . setParametersModel . setParametersOdeSolver . setPossibleArms . setRange-set . setSampleTime . setSamplings-set . setShowProcess . setSigmaInter-set . setSigmaSlope-set . setTau . setTimeDose-set . setTinf . setTotalNumberOfIndividuals . setTotalSize-set . show . showArmData . showConstraints . showDesigns . showFims . showStatisticalModelStandardErrors . summary . summaryArmData . 
Some associated R codes: Administration.R . AdministrationConstraint.R . Arm.R . BayesianFim.R . Combined1.R . Combined1c.R . Combined2.R . Combined2c.R . Constant.R . Constraint.R . ContinuousConstraint.R . Design.R . DesignConstraint.R . DiscreteConstraint.R . Distribution.R . FedorovWynnAlgorithm.R . FillLibraryOfModels.R . Fim.R . IndividualFim.R . LibraryOfModels.R . LogNormalDistribution.R . Model.R . ModelEquations.R . ModelError.R . ModelInfusionEquations.R . ModelInfusionODEquations.R . ModelODEquations.R . ModelParameter.R . ModelVariable.R . MultiplicativeAlgorithm.R . NormalDistribution.R . Optimization.R . PDModel.R . PFIM-package.R . PFIMProject.R . PGBOAlgorithm.R . PKModel.R . PKPDModel.R . PSOAlgorithm.R . PopulationFim.R . Proportional.R . ProportionalC.R . ReportAndPlots.R . Response.R . SamplingConstraint.R . SamplingTimes.R . SimplexAlgorithm.R . StandardDistribution.R . StatisticalModel.R . globals.R .  Full PFIM package functions and examples
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