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PDXpower
View on CRAN: Click
here
Download and install PDXpower package within the R console
Install from CRAN:
install.packages("PDXpower")
Install from Github:
library("remotes")
install_github("cran/PDXpower")
Install by package version:
library("remotes")
install_version("PDXpower", "1.0.0")
Attach the package and use:
library("PDXpower")
Maintained by
Shanpeng Li
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2024-03-11
Latest Update: 2024-03-11
Description:
Conduct simulation-based customized power calculation
for clustered time to event data in a mixed crossed/nested design,
where a number of cell lines and a number of mice within each cell line are considered to achieve a desired statistical power,
motivated by Eckel-Passow and colleagues (2021) .
This package provides two commonly used models for powering a design, linear mixed effects and Cox frailty model. Both models account for
within-subject (cell line) correlation while holding different distributional assumptions about the outcome.
Alternatively, the counterparts of fixed effects model are also available, which produces similar estimates of statistical power.
How to cite:
Shanpeng Li (2024). PDXpower: Time to Event Outcome in Experimental Designs of Pre-Clinical
Studies. R package version 1.0.0, https://cran.r-project.org/web/packages/PDXpower
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