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PANACEA
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Download and install PANACEA package within the R console
Install from CRAN:
install.packages("PANACEA")
Install from Github:
library("remotes")
install_github("cran/PANACEA")
Install by package version:
library("remotes")
install_version("PANACEA", "1.0.1")
Attach the package and use:
library("PANACEA")
Maintained by
Ege Ulgen
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2023-05-02
Latest Update: 2023-08-19
Description:
Identification of the most appropriate pharmacotherapy for each
patient based on genomic alterations is a major challenge in personalized
oncology. 'PANACEA' is a collection of personalized anti-cancer drug
prioritization approaches utilizing network methods. The methods utilize
personalized "driverness" scores from 'driveR' to rank drugs, mapping these
onto a protein-protein interaction network. The "distance-based" method
scores each drug based on these scores and distances between drugs and genes
to rank given drugs. The "RWR" method propagates these scores via a
random-walk with restart framework to rank the drugs. The methods are
described in detail in Ulgen E, Ozisik O, Sezerman OU. 2023. PANACEA:
network-based methods for pharmacotherapy prioritization in personalized
oncology. Bioinformatics .
How to cite:
Ege Ulgen (2023). PANACEA: Personalized Network-Based Anti-Cancer Therapy Evaluation. R package version 1.0.1, https://cran.r-project.org/web/packages/PANACEA
Previous versions and publish date:
1.0.0 (2023-05-02 23:10)
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