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MultisiteMediation  

Causal Mediation Analysis in Multisite Trials
View on CRAN: Click here


Download and install MultisiteMediation package within the R console
Install from CRAN:
install.packages("MultisiteMediation")

Install from Github:
library("remotes")
install_github("cran/MultisiteMediation")

Install by package version:
library("remotes")
install_version("MultisiteMediation", "0.0.4")



Attach the package and use:
library("MultisiteMediation")
Maintained by
Xu Qin
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2017-02-26
Latest Update: 2021-09-05
Description:
Multisite causal mediation analysis using the methods proposed by Qin and Hong (2017) , Qin, Hong, Deutsch, and Bein (2019) , and Qin, Deutsch, and Hong (2021) . It enables causal mediation analysis in multisite trials, in which individuals are assigned to a treatment or a control group at each site. It allows for estimation and hypothesis testing for not only the population average but also the between-site variance of direct and indirect effects transmitted through one single mediator or two concurrent (conditionally independent) mediators. This strategy conveniently relaxes the assumption of no treatment-by-mediator interaction while greatly simplifying the outcome model specification without invoking strong distributional assumptions. This package also provides a function that can further incorporate a sample weight and a nonresponse weight for multisite causal mediation analysis in the presence of complex sample and survey designs and non-random nonresponse, to enhance both the internal validity and external validity. The package also provides a weighting-based balance checking function for assessing the remaining overt bias.
How to cite:
Xu Qin (2017). MultisiteMediation: Causal Mediation Analysis in Multisite Trials. R package version 0.0.4, https://cran.r-project.org/web/packages/MultisiteMediation. Accessed 20 Aug. 2026.
Previous versions and publish date:
0.0.1 (2017-02-26 19:56), 0.0.2 (2018-06-15 09:28), 0.0.3 (2020-05-27 16:20), (2026-07-09 08:11)
Other packages that cited MultisiteMediation R package
View MultisiteMediation citation profile
Other R packages that MultisiteMediation depends, imports, suggests or enhances
Complete documentation for MultisiteMediation
Functions, R codes and Examples using the MultisiteMediation R package
Some associated functions: balance . msmediate.concurrent . msmediate . msmediate.weights . sim . sim.weights . vartest.msmediate.concurrent . vartest.msmediate . vartest.msmediate.weights . 
Some associated R codes: msmediate.R .  Full MultisiteMediation package functions and examples
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