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MetaEntropy  

Functional Shannon Entropy for Virome Mutational Analysis
View on CRAN: Click here


Download and install MetaEntropy package within the R console
Install from CRAN:
install.packages("MetaEntropy")

Install from Github:
library("remotes")
install_github("cran/MetaEntropy")

Install by package version:
library("remotes")
install_version("MetaEntropy", "1.2")



Attach the package and use:
library("MetaEntropy")
Maintained by
Leandro Roberto Jones
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2026-03-03
Latest Update: 2026-03-03
Description:
Estimates Shannon entropy, per gene and per genomic position, associated with non-synonymous mutation frequencies in viral populations, such as wastewater samples or quasispecies. By categorizing amino acids based on their physicochemical properties, the package determines whether a mutation is functionally disruptive or neutral. Provides normalized values (0-1 scale) to facilitate the direct comparison of different genomic positions or total functional entropy across multiple metagenomes. Designed to analyze mutational data using tabular 'Single Nucleotide Variant' (SNV) frequency tables generated by variant callers (e.g., 'iVar' or 'LoFreq'), operating independently of consensus sequence estimation and multiple sequence alignment.
How to cite:
Leandro Roberto Jones (2026). MetaEntropy: Functional Shannon Entropy for Virome Mutational Analysis. R package version 1.2, https://cran.r-project.org/web/packages/MetaEntropy. Accessed 21 Aug. 2026.
Previous versions and publish date:
1.2 (2026-03-03 11:00), (2026-07-09 08:10)
Other packages that cited MetaEntropy R package
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Complete documentation for MetaEntropy
Functions, R codes and Examples using the MetaEntropy R package
Full MetaEntropy package functions and examples
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