Other packages > Find by keyword >

LEANR  

Finds "Local Subnetworks" Within an Interaction Network which Show Enrichment for Differentially Expressed Genes
View on CRAN: Click here


Download and install LEANR package within the R console
Install from CRAN:
install.packages("LEANR")

Install from Github:
library("remotes")
install_github("cran/LEANR")

Install by package version:
library("remotes")
install_version("LEANR", "1.4.9")



Attach the package and use:
library("LEANR")
Maintained by
Frederik Gwinner
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2016-11-12
Latest Update:
Description:
Implements the method described in "Network-based analysis of omics data: The LEAN method" [Gwinner Boulday (2016) ] Given a protein interaction network and a list of p-values describing a measure of interest (as e.g. differential gene expression) this method computes an enrichment p-value for the protein neighborhood of each gene and compares it to a background distribution of randomly drawn p-values. The resulting scores are corrected for multiple testing and significant hits are returned in tabular format.
How to cite:
Frederik Gwinner (2016). LEANR: Finds "Local Subnetworks" Within an Interaction Network which Show Enrichment for Differentially Expressed Genes. R package version 1.4.9, https://cran.r-project.org/web/packages/LEANR. Accessed 10 Mar. 2026.
Previous versions and publish date:
1.4.9 (2016-11-12 15:47)
Other packages that cited LEANR R package
View LEANR citation profile
Other R packages that LEANR depends, imports, suggests or enhances
Functions, R codes and Examples using the LEANR R package
Some associated functions: CCM.pvals . LEANR-package . g2 . g_red . gene.annots . gene.list.scores . get.ls.info . pvals_red . run.lean . subnet.simulation . write.ls.to.sif . 
Some associated R codes: leanr_method.R .  Full LEANR package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

envirem  
Generation of ENVIREM Variables
Generation of bioclimatic rasters that are complementary to the typical 19 bioclim variables. ...
Download / Learn more Package Citations See dependency  
gena  
Genetic Algorithm and Particle Swarm Optimization
Implements genetic algorithm and particle swarm algorithm for real-valued functions. Various modific ...
Download / Learn more Package Citations See dependency  
plyr  
Tools for Splitting, Applying and Combining Data
A set of tools that solves a common set of problems: you need to break a big problem down into mana ...
Download / Learn more Package Citations See dependency  
nextGenShinyApps  
Craft Exceptional 'R Shiny' Applications and Dashboards with Novel Responsive Tools
Nove responsive tools for designing and developing 'Shiny' dashboards and applications. The scripts ...
Download / Learn more Package Citations See dependency  

26,293

R Packages

225,784

Dependencies

70,376

Author Associations

26,294

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA