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IOBR  

Immune Oncology Biological Research
View on CRAN: Click here


Download and install IOBR package within the R console
Install from CRAN:
install.packages("IOBR")

Install from Github:
library("remotes")
install_github("cran/IOBR")

Install by package version:
library("remotes")
install_version("IOBR", "2.2.3")



Attach the package and use:
library("IOBR")
Maintained by
Shixiang Wang
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2026-04-22
Latest Update: 2026-04-22
Description:
Provides six modules for tumor microenvironment (TME) analysis based on multi-omics data. These modules cover data preprocessing, TME estimation, TME infiltrating patterns, cellular interactions, genome and TME interaction, and visualization for TME relevant features, as well as modelling based on key features. It integrates multiple microenvironmental analysis algorithms and signature estimation methods, simplifying the analysis and downstream visualization of the TME. In addition to providing a quick and easy way to construct gene signatures from single-cell RNA-seq data, it also provides a way to construct a reference matrix for TME deconvolution from single-cell RNA-seq data. The analysis pipeline and feature visualization are user-friendly and provide a comprehensive description of the complex TME, offering insights into tumour-immune interactions (Zeng D, et al. (2024) <doi:10.1016/j.crmeth.2024.100910>.Fang Y, et al. (2025) <doi:10.1002/mdr2.70001>).
How to cite:
Shixiang Wang (2026). IOBR: Immune Oncology Biological Research. R package version 2.2.3, https://cran.r-project.org/web/packages/IOBR. Accessed 12 Oct. 2026.
Previous versions and publish date:
2.2.0 (2026-04-22 16:00), 2.2.1 (2026-05-15 18:00), 2.2.2 (2026-05-25 18:10), (2026-07-09 08:07)
Other packages that cited IOBR R package
View IOBR citation profile
Other R packages that IOBR depends, imports, suggests or enhances
Complete documentation for IOBR
Functions, R codes and Examples using the IOBR R package
Full IOBR package functions and examples
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