Other packages > Find by keyword >

HetSeq  

Identifying Modulators of Cellular Responses Leveraging Intercellular Heterogeneity
View on CRAN: Click here


Download and install HetSeq package within the R console
Install from CRAN:
install.packages("HetSeq")

Install from Github:
library("remotes")
install_github("cran/HetSeq")

Install by package version:
library("remotes")
install_version("HetSeq", "0.1.0")



Attach the package and use:
library("HetSeq")
Maintained by
Kevin Berg
[Scholar Profile | Author Map]
First Published: 2025-02-03
Latest Update: 2025-02-03
Description:
Cellular responses to perturbations are highly heterogeneous and depend largely on the initial state of cells. Connecting post-perturbation cells via cellular trajectories to untreated cells (e.g. by leveraging metabolic labeling information) enables exploitation of intercellular heterogeneity as a combined knock-down and overexpression screen to identify pathway modulators, termed Heterogeneity-seq (see 'Berg et al' <doi:10.1101/2024.10.28.620481>). This package contains functions to generate cellular trajectories based on scSLAM-seq (single-cell, thiol-(SH)-linked alkylation of RNA for metabolic labelling sequencing) time courses, functions to identify pathway modulators and to visualize the results.
How to cite:
Kevin Berg (2025). HetSeq: Identifying Modulators of Cellular Responses Leveraging Intercellular Heterogeneity. R package version 0.1.0, https://cran.r-project.org/web/packages/HetSeq. Accessed 03 Apr. 2025.
Previous versions and publish date:
No previous versions
Other packages that cited HetSeq R package
View HetSeq citation profile
Other R packages that HetSeq depends, imports, suggests or enhances
Complete documentation for HetSeq
Functions, R codes and Examples using the HetSeq R package
Full HetSeq package functions and examples
Downloads during the last 30 days
03/0403/0503/0603/0703/0903/1003/1103/1203/1303/1403/1503/1603/1703/1803/1903/2003/2103/2203/2303/2403/2503/2603/2703/2803/2903/3003/3104/01Downloads for HetSeq012345678910111213TrendBars

Today's Hot Picks in Authors and Packages

RI2by2  
Randomization Inference for Treatment Effects on a Binary Outcome
Computes attributable effects based confidence interval, permutation test confidence interval, or as ...
Download / Learn more Package Citations See dependency  
jointDiag  
Joint Approximate Diagonalization of a Set of Square Matrices
Different algorithms to perform approximate joint diagonalization of a finite set of square matrice ...
Download / Learn more Package Citations See dependency  
RPMG  
Graphical User Interface (GUI) for Interactive R Analysis Sessions
Really Poor Man's Graphical User Interface, used to create interactive R analysis sessions with simp ...
Download / Learn more Package Citations See dependency  
RobustANOVA  
Robust One-Way ANOVA Tests under Heteroscedasticity and Nonnormality
Robust tests (RW, RPB and RGF) are provided for testing the equality of several long-tailed symmetri ...
Download / Learn more Package Citations See dependency  
RZooRoH  
Partitioning of Individual Autozygosity into Multiple Homozygous-by-Descent Classes
Functions to identify Homozygous-by-Descent (HBD) segments associated with runs of homozygosity (ROH ...
Download / Learn more Package Citations See dependency  
automl  
Deep Learning with Metaheuristic
Fits from simple regression to highly customizable deep neural networks either with gradient descen ...
Download / Learn more Package Citations See dependency  

23,990

R Packages

207,311

Dependencies

64,809

Author Associations

23,991

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA